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Merck
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文件

860455P

Avanti

N-C12-deoxysphingosine

N-lauroyl-1-deoxysphingosine (m18:1/12:0), powder

别名:

N-dodecanoyl-1-deoxysphing-4-enine (m18:1/12:0); N-C12-1-deoxyCer; 110992

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About This Item

经验公式（希尔记法）:
C30H59NO2
CAS号:
1246298-54-3
分子量:
465.79
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (860455P-1mg)
pkg of 1 × 5 mg (860455P-5mg)

製造商／商標名

Avanti Research™ - A Croda Brand 860455P

脂質類型

sphingolipids
bioactive lipids

運輸包裝

dry ice

儲存溫度

−20°C

相关类别

一般說明

N-C12-deoxysphingosine, also known as 1-deoxydihydroceramide (1-deoxyDHCer) is, the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.

應用

N-C12-deoxysphingosine has been used as a standard in the quantitation of atypical sphingoid bases in biological samples by reverse-phase liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS/MS).

包裝

5 mL Amber Glass Screw Cap Vial (860455P-1mg)
5 mL Amber Glass Screw Cap Vial (860455P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

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Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that
Sarah T Pruett et al.
Journal of lipid research, 49(8), 1621-1639 (2008-05-24)
"Sphingosin" was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of "lipides derived from sphingosine as sphingolipides." This category of amino alcohols is now

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