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Merck

860400P

Avanti

14:0 PS-d54

Avanti Research - A Croda Brand 860400P, powder

别名:

1,2-dimyristoyl-d54-sn-glycero-3-[phospho-L-serine] (sodium salt)

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About This Item

经验公式(希尔记法):
C34H11NO10PNaD54
分子量:
756.18
分類程式碼代碼:
12352100
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (860400P-10mg)
pkg of 1 × 25 mg (860400P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 860400P

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H])C([2H]

一般說明

1,2-dimyristoyl-d54-sn-glycero-3-[phospho-L-serine] (14:0 PS-d54) is a deuterated phosphoserine (PS) wherein 54 protons of dimyristoyl are replaced by deuterium.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

應用

1,2-dimyristoyl-d54-sn-glycero-3-[phospho-L-serine] (14:0 PS-d54) has been used to interact with lipid A to study the unspecific interaction of a phospholipid membrane with endotoxins. It has also been used as an apolar lipid internal standard for mass spectrometry.

包裝

5 mL Amber Glass Screw Cap Vial (860400P-10mg)
5 mL Amber Glass Screw Cap Vial (860400P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Lipopolysaccharide-binding protein-mediated interaction of lipid A from different origin with phospholipid membranes Invited Lecture
Gutsmann T, et al.
Physical Chemistry Chemical Physics, 2(20), 4521-4528 (2000)
Dominique Mias-Lucquin et al.
Journal of structural biology, 209(1), 107411-107411 (2019-11-07)
Dystrophin is a large intracellular protein that prevents sarcolemmal ruptures by providing a mechanical link between the intracellular actin cytoskeleton and the transmembrane dystroglycan complex. Dystrophin deficiency leads to the severe muscle wasting disease Duchenne Muscular Dystrophy and the milder
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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