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Merck

860080P

Avanti

18:1 Lactosyl PE

Avanti Research - A Croda Brand

别名:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt)

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About This Item

经验公式(希尔记法):
C53H103N2O18P
分子量:
1087.36
分類程式碼代碼:
51191904
NACRES:
NA.25

描述

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt)

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 25 mg (860080P-25mg)
pkg of 1 × 5 mg (860080P-5mg)
pkg of 1 × 50 mg (860080P-50mg)

製造商/商標名

Avanti Research - A Croda Brand

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP(OCCNCC(O)C(O)[C@@H]([C@H](O)CO)O[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

InChI

1S/C53H100NO18P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-46(59)67-40-42(70-47(60)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)41-69-73(65,66)68-36-35-54-37-43(57)48(61)52(44(58)38-55)72-53-51(64)50(63)49(62)45(39-56)71-53;/h17-20,42-45,48-58,61-64H,3-16,21-41H2,1-2H3,(H,65,66);1H3/b19-17-,20-18-;/t42-,43?,44?,45?,48?,49+,50?,51?,52-,53+;/m1./s1

InChI 密鑰

POKKWVSABAYGGQ-GDPHZLNSSA-N

一般說明

Phosphatidylethanolamine is a phospholipid and is bound to the biological membranes.

應用

18:1 Lactosyl PE is suitable for the preparation of donor liposomes.

生化/生理作用

Phosphatidylethanolamine has a tendency of binding to proteins and forming a complex of phosphatidylethanolamine-binding protein (PEBP). The binding of an isoform of phosphatidylethanolamine (1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine) to Peroxisome Proliferator-Activated Receptors (PPARs) helps in regulating genes involved in lipid metabolism.

包裝

5 mL Clear Glass Sealed Ampule (860080P-25mg)
5 mL Clear Glass Sealed Ampule (860080P-50mg)
5 mL Clear Glass Sealed Ampule (860080P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析证书(COA)

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Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction
Banfield M J, et al.
Structure, 6(10), 1245-1254 (1998)
A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7
Bockelmann S, et al.
Journal of Lipid Research, 59(3), 515-530 (2018)
Phosphatidylcholine?s functions beyond that of a membrane brick
Furse S and De Kroon AIPM
Molecular Membrane Biology, 32(4), 117-119 (2015)
Svenja Bockelmann et al.
Journal of lipid research, 59(3), 515-530 (2018-01-19)
Ceramides are central intermediates of sphingolipid metabolism with dual roles as mediators of cellular stress signaling and mitochondrial apoptosis. How ceramides exert their cytotoxic effects is unclear and their poor solubility in water hampers a search for specific protein interaction

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