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Merck

858125C

Avanti

18:1 Lyso PG

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

别名:

1-oleoy-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:1(9Z)/0:0); 110714

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About This Item

经验公式(希尔记法):
C24H46O9PNa
分子量:
532.58
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)

形狀

liquid

包裝

pkg of 5 × 4 mL (858125C-500mg)

製造商/商標名

Avanti Research - A Croda Brand 858125C

濃度

25 mg/mL (858125C-500mg)

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are produced in γ-proteobacteria by lipoprotein acyltransferase activity. These lipids are found in minimal amount in normal bacterial membranes.

應用

18:1 Lyso PG has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.

生化/生理作用

Lyso phosphoglycerol (Lyso PG) and acyl-CoA acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) to synthesize phosphoglycerol. Lyso-phospholipids are nonbilayer-forming lipids. Accumulation of lysophospholipids in bacterial membranes disrupt the membrane integrity due to its detergent- like physical property.

包裝

5 mL Clear Glass Sealed Ampule (858125C-500mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

也與該產品經常一起購買

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Expression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis
Chadwick A, et al.
Protein Expression and Purification, 107, 35-42 (2015)
Substrate selectivity of lysophospholipid transporter LplT involved in membrane phospholipid remodeling in Escherichia coli
Lin Y, et al.
The Journal of Biological Chemistry, 291(5), 2136-2149 (2016)
Hideo Shindou et al.
The Journal of biological chemistry, 284(1), 1-5 (2008-08-23)
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
Comprehensive untargeted lipidomic analysis using core-shell C30 particle column and high field orbitrap mass spectrometer
Narvaez-Rivas M and Zhang Q
Journal of Chromatography A, 1440, 123-134 (2016)
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate

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