850459C

16:0-20:4 PC

Avanti Research^™ - A Croda Brand

• 别名: 1-hexadecanoyl-2--(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; PAPC; PC(16:0/20:4(5Z,8Z,11Z,14Z))
• 经验公式（希尔记法）: C₄₄H₈₀NO₈P
• CAS号: 35418-58-7
• 分子量: 782.08
• 分類程式碼代碼: 51191904
• NACRES: NA.25

属性

• 描述: 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine, chloroform
• 化驗: >99% (TLC)
• 形狀: liquid
• 包裝: pkg of 1 × 2.5 mL (850459C-25mg); pkg of 2 × 4 mL (850459C-200mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand
• 濃度: 10 mg/mL (850459C-25mg); 25 mg/mL (850459C-200mg)
• 脂質類型: cardiolipins; phospholipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• InChI: 1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-21-22-23-25-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-24-19-17-15-13-11-9-7-2/h14,16,20-21,23,25,28,30,42H,6-13,15,17-19,22,24,26-27,29,31-41H2,1-5H3/b16-14-,21-20-,25-23-,30-28-/t42-/m1/s1
• InChI 密鑰: PUDHBQQGURLBGJ-IVFHWKNFSA-N

说明

一般說明

Phosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway.

應用

16:0-20:4 PC is suitable for use:

• in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysis
• in liposome preparation for the treatment of organoid
• as antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids

生化／生理作用

Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.

包裝

5 mL Clear Glass Sealed Ampule (850459C-200mg)

5 mL Clear Glass Sealed Ampule (850459C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 防範說明: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危險分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 標靶器官: Central nervous system, Liver,Kidney
• 儲存類別代碼: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: does not flash
• 閃點（°C）: does not flash