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850445C

Avanti

14:0-16:0 PC

1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine, chloroform

别名:

1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; MPPC; PC(14:0/16:0)

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About This Item

经验公式（希尔记法）:
C38H76NO8P
CAS号:
69525-80-0
分子量:
705.99
MDL號碼:
MFCD00674322
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (850445C-25mg)
pkg of 1 × 20 mL (850445C-500mg)

製造商／商標名

Avanti Research™ - A Croda Brand 850445C

濃度

10 mg/mL (850445C-25mg)
25 mg/mL (850445C-500mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1

InChI 密鑰

RFVFQQWKPSOBED-PSXMRANNSA-N

相关类别

一般說明

Phosphatidylcholine (PC) is dietary source of choline. 14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) is a water-soluble lysolipid. 14:0-16:0 PC is a symmetrical phosphatidylcholine.

應用

14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) has been used to generate Wnt3a liposomes. It has also been used as a calibration standard for lipidomic analysis by liquid chromatography–tandem mass spectrometry (LC-MS). It may be used in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC).

生化／生理作用

Phosphatidylcholine (PC) is involved in the fusion and transport of membranes. It is known to play a vital role in endocytosis and the catalytic activity of enzymes.

包裝

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850445C-500mg)
5 mL Clear Glass Sealed Ampule (850445C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

標靶器官

Liver,Kidney, Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

does not flash

閃點（°C）

does not flash

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jeffrey K Mills et al.
Biochimica et biophysica acta, 1716(2), 77-96 (2005-10-12)
The enhanced permeability of lipid bilayer membranes at their gel-to-liquid phase transition has been explained using a "bilayer lipid heterogeneity" model, postulating leaky interfacial regions between still solid and melting liquid phases. The addition of lysolipid to dipalmitoylphosphatidylcholine bilayers dramatically
Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Li-Juan Zhao et al.
Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)
Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu
Nathan T Morrell et al.
PloS one, 3(8), e2930-e2930 (2008-08-14)
Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and
Dana K Shaw et al.
Nature communications, 8, 14401-14401 (2017-02-15)
The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that infection-derived lipids

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