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化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 2.5 mL (850399C-25mg)
製造商/商標名
Avanti Research™ - A Croda Brand 850399C
濃度
10 mg/mL (850399C-25mg)
脂質類型
cardiolipins
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C56H108NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-48-55(58)62-52-54(53-64-66(60,61)63-51-50-57(3,4)5)65-56(59)49-47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,54H,6-19,24-53H2,1-5H3/b22-20-,23-21-/t54-/m1/s1
InChI 密鑰
REWNAIYQZZOESC-CGKZWXATSA-N
一般說明
Phosphatidylcholine (PC) is a zwitterionic glycerophospholipid. PC constitutes the major phospholipid in the eukaryotic membrane. Among bacteria, only 10% has PC in their membrane.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
應用
24:1 (Cis) PC is suitable for use as a phospholipid (PL) standard for lipid profiling of phosphatidylcholine by electrospray ionization mass spectrometry (ESI-MS/MS).
24:1 (Cis) PC has been used:
- in the preparation of multivesicular liposomes (DepoFoam) formulation with protein or peptide drugs
- in the formation of planar bilayer lipid membranes
- for analyzing the phase transition of giant unilamellar dinervonoylphosphocholine (DNPC) vesicles by N-4-nitrobenz-2-oxa-1,3-diazol (NBD)-labelled fluorophore in confocal microscopy
生化/生理作用
24:1 (Cis) PC is a synthetic lipid.
Phosphatidylcholine (PC) is essential for the structure and functions of eukaryotic membranes. PC is essential for very low-density lipoprotein synthesis in liver cells. PC is the substrate for sphingomyelin. PC is the major source of cell signaling molecules. PC is the structural component of many human parasites and helps in cell invasion.
包裝
5 mL Clear Glass Sealed Ampule (850399C-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
水污染物質分類(WGK)
WGK 3
Extraction and profiling of plant polar glycerol lipids
Bio-protocol (2016)
Observation of the main phase transition of dinervonoylphosphocholine giant liposomes by fluorescence microscopy
Biochimica et Biophysica Acta - Biomembranes, 1713(2), 83-91 (2005)
Lipid dependence of the channel properties of a colicin E1-lipid toroidal pore
The Journal of Biological Chemistry, 281(20), 14408-14416 (2006)
[TM="DepoFoam"] technology: a vehicle for controlled delivery of protein and peptide drugs
Journal of Controlled Release : Official Journal of the Controlled Release Society, 64(1-3), 155-166 (2000)
Activating and deactivating roles of lipid bilayers on the Ca2+-ATPase/phospholamban complex
Biochemistry, 50(47), 10367-10374 (2011)
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