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Merck

850399C

Avanti

24:1 (Cis) PC

1,2-dinervonoyl-sn-glycero-3-phosphocholine, chloroform

别名:

1,2-di-(15Z-tetracosenoyl)-sn-glycero-3-phosphocholine; PC(24:1(15Z)/24:1(15Z)); 110930

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About This Item

经验公式(希尔记法):
C56H108NO8P
CAS号:
分子量:
954.43
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (850399C-25mg)

製造商/商標名

Avanti Research - A Croda Brand 850399C

濃度

10 mg/mL (850399C-25mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

InChI

1S/C56H108NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-48-55(58)62-52-54(53-64-66(60,61)63-51-50-57(3,4)5)65-56(59)49-47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,54H,6-19,24-53H2,1-5H3/b22-20-,23-21-/t54-/m1/s1

InChI 密鑰

REWNAIYQZZOESC-CGKZWXATSA-N

一般說明

Phosphatidylcholine (PC) is a zwitterionic glycerophospholipid. PC constitutes the major phospholipid in the eukaryotic membrane. Among bacteria, only 10% has PC in their membrane.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

應用

24:1 (Cis) PC is suitable for use as a phospholipid (PL) standard for lipid profiling of phosphatidylcholine by electrospray ionization mass spectrometry (ESI-MS/MS).
24:1 (Cis) PC has been used:
  • in the preparation of multivesicular liposomes (DepoFoam) formulation with protein or peptide drugs
  • in the formation of planar bilayer lipid membranes
  • for analyzing the phase transition of giant unilamellar dinervonoylphosphocholine (DNPC) vesicles by N-4-nitrobenz-2-oxa-1,3-diazol (NBD)-labelled fluorophore in confocal microscopy

生化/生理作用

24:1 (Cis) PC is a synthetic lipid.
Phosphatidylcholine (PC) is essential for the structure and functions of eukaryotic membranes. PC is essential for very low-density lipoprotein synthesis in liver cells. PC is the substrate for sphingomyelin. PC is the major source of cell signaling molecules. PC is the structural component of many human parasites and helps in cell invasion.

包裝

5 mL Clear Glass Sealed Ampule (850399C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

水污染物質分類(WGK)

WGK 3


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分析证书(COA)

Lot/Batch Number

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访问文档库

Extraction and profiling of plant polar glycerol lipids
Liu Yu and Wang X
Bio-protocol (2016)
Observation of the main phase transition of dinervonoylphosphocholine giant liposomes by fluorescence microscopy
Metso AJ, et al.
Biochimica et Biophysica Acta - Biomembranes, 1713(2), 83-91 (2005)
Lipid dependence of the channel properties of a colicin E1-lipid toroidal pore
Sobko AA, et al.
The Journal of Biological Chemistry, 281(20), 14408-14416 (2006)
[TM="DepoFoam"] technology: a vehicle for controlled delivery of protein and peptide drugs
Ye Q, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 64(1-3), 155-166 (2000)
Activating and deactivating roles of lipid bilayers on the Ca2+-ATPase/phospholamban complex
Gustavsson M, et al.
Biochemistry, 50(47), 10367-10374 (2011)

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