推荐产品
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 2.5 mL (850346C-25mg)
pkg of 2 × 4 mL (850346C-200mg)
製造商／商標名
Avanti Polar Lipids 850346C
濃度
10 mg/mL (850346C-25mg)
25 mg/mL (850346C-200mg)
脂質類型
cardiolipins
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
應用
14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.
生化／生理作用
Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.
包裝
5 mL Clear Glass Sealed Ampule (850346C-200mg)
5 mL Clear Glass Sealed Ampule (850346C-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
Phosphatidylcholine and cell death
Cui Z and Houweling M
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1585(2-3), 87-96 (2002)
Integrative Medicine - E-Book (2017)
Bilayer thickness and curvature influence binding and insertion of a pHLIP peptide
Karabadzhak AG, et al.
Biophysical Journal, 114(9), 2107-2115 (2018)
The Membranes of Cells (2016)
Interference of phosphatidylcholines with in vitro cell proliferation?no flock without black sheep
Werlein A, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(7), 1599-1608 (2015)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门