推荐产品
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 2.5 mL (850320C-25mg)
製造商／商標名
Avanti Polar Lipids 850320C
濃度
10 mg/mL (850320C-25mg)
脂質類型
cardiolipins
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C26H52NO8P/c1-6-8-10-12-14-16-18-25(28)32-22-24(35-26(29)19-17-15-13-11-9-7-2)23-34-36(30,31)33-21-20-27(3,4)5/h24H,6-23H2,1-5H3/t24-/m1/s1
InChI 密鑰
CKGVBFQDYSPMSY-XMMPIXPASA-N
一般說明
Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the membrane. The fatty acids in the sn-1 and sn-2 positions of PCs are covalently attached to a glycerol with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
應用
09:0 PC (1,2-dinonanoyl-sn-glycero-3-phosphocholine) may be used:
- as an internal standard for phospholipid extraction from renal tissues using liquid chromatography coupled to electrospray ionization tandem mass spectrometry
- as a supplement in sample mixture as internal standard for liquid-liquid extraction and to spike the samples in order to determine lipid extract from fibroblasts by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
- an internal standard to spike frozen aliquots of plasma in liquid chromatography with tandem mass spectrometry (LC-MS-MS)
生化／生理作用
The physical properties of membranes can be modulated with the help of fatty acyl configuration of phosphatidylcholines (PCs). They serve as a major source for eicosanoids.
包裝
5 mL Clear Glass Sealed Ampule (850320C-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
does not flash
閃點（°C）
does not flash
Florian Gruber et al.
Journal of lipid research, 53(6), 1232-1242 (2012-03-15)
Oxidized phospholipids (OxPLs) are increasingly recognized as signaling mediators that are not only markers of oxidative stress but are also "makers" of pathology relevant to disease pathogenesis. Understanding the biological role of individual molecular species of OxPLs requires the knowledge
Zahra Solati et al.
PloS one, 13(4), e0195172-e0195172 (2018-04-24)
The aim of this study was to determine the individual oxidized phosphatidylcholine (OxPC) molecules generated during renal ischemia/ reperfusion (I/R) injury. Kidney ischemia was induced in male Sprague-Dawley rats by clamping the left renal pedicle for 45 min followed by
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