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Merck

840052P

Avanti

Heart PC

Avanti Research - A Croda Brand 840052P, powder

别名:

L-α-phosphatidylcholine (Heart, Bovine)

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About This Item

CAS号:
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 2 × 100 mg (840052P-200mg)
pkg of 1 × 25 mg (840052P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 840052P

脂質類型

phosphoglycerides
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI 密鑰

JLPULHDHAOZNQI-ZTIMHPMXSA-N

一般說明

Contains ~40% plasmalogen ether lipid
Phosphatidylcholine (PC) is a glycerophospholipid present abundantly in eukaryotes. It comprises 40-50% of the total phospholipid content in the cell membrane. PC is synthesized by the Kennedy pathway.

應用

Heart PC has been used in the preparation of phospholipid reference mixture.

生化/生理作用

Phosphatidylcholine (PC) in the liver is responsible for the production of very low density lipoproteins (VLDL). It is an important source for the formation of lipid mediators and secondary messengers.

包裝

5 mL Clear Glass Sealed Ampule (840052P-200mg)
5 mL Clear Glass Sealed Ampule (840052P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5(6), 16787-16787 (2015)
Expression of Shiga toxin 2e glycosphingolipid receptors of primary porcine brain endothelial cells and toxin-mediated breakdown of the blood-brain barrier
Meisen I, et al.
Glycobiology, 23(6), 745-759 (2013)
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.
van der Veen J N, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(9 Pt B), 1558-1558 (2017)
Marianne S Jurkowitz et al.
Biochimica et biophysica acta, 1848(2), 742-751 (2014-12-03)
Lysoplasmalogenase catalyzes hydrolytic cleavage of the vinyl-ether bond of lysoplasmalogen to yield fatty aldehyde and glycerophospho-ethanolamine or glycerophospho-choline. We recently purified lysoplasmalogenase from rat liver microsomes and identified the protein as TMEM86B, an integral membrane protein that is a member
Ivan U Kouzel et al.
Journal of lipid research, 54(3), 692-710 (2012-12-19)
Glycosphingolipids (GSLs) of the globo-series constitute specific receptors for Shiga toxins (Stxs) released by certain types of pathogenic Escherichia coli strains. Stx-loaded leukocytes may act as transporter cells in the blood and transfer the toxin to endothelial target cells. Therefore

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