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化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (810209X-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand 810209X
濃度
1 mg/mL (810209X-1mg)
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1
InChI 密鑰
HZIRBXILQRLFIK-VPZZKNKNSA-N
一般說明
C6-NBD ceramide is a fluorescent labelled compound, known to be useful for the detection of enzymatic action. C6-NBD ceramide is preferred over radioactive compounds.
應用
C6-NBD Ceramide is suitable as a substrate for sphingomyelin synthase activity assay.
生化／生理作用
Sphingolipid metabolism yields ceramide as one of the products. The family of ceramide synthases catalyses its synthesis. The ceramides differ in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.
包裝
5 mL Amber Glass Screw Cap Vial (810209X-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 1 - STOT SE 3
標靶器官
Central nervous system, Eyes,Central nervous system, Liver,Kidney
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
Handbook of Glycosyltransferases and Related Genes, 5-5 (2011)
Mammalian ceramide synthases
Levy M and Futerman AH
IUBMB Life, 62(5), 347-356 (2010)
A role for ceramides, but not sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes
Park M, et al.
The Journal of Biological Chemistry, 291(46), 23978-23988 (2016)
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