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Merck
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Key Documents

810142C

Avanti

4ME 16:0 NBD PE (NBD-DPhPE)

1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt), chloroform

别名:

NBD-DPhPE

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About This Item

经验公式(希尔记法):
C51H94N5O11P
分子量:
984.29
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (810142C-1mg)

製造商/商標名

Avanti Polar Lipids 810142C

濃度

1 mg/mL (810142C-1mg)

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

4ME 16:0 NBD PE (NBD-DPhPE) is a headgroup labeled fluorescent phospholipid.
NBD-DPhPE preferentially partitions, although not entirely, into the fluid phase of the cell membrane rather than the more ordered cholesterol and sphingolipid-enriched microdomain known as a lipid "raft."NBD-DSPE preferentially partitions, although not entirely, into the more ordered cholesterol and sphingolipid-enriched microdomain known as a lipid "raft." - Personal communication, Dr. Erwin London, SUNY-Stony Brook

應用

4ME 16:0 NBD PE (NBD-DPhPE) or 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt) may be used for fluorescence resonance energy transfer (FRET)experiments to determine raft affinity.

包裝

5 mL Amber Glass Screw Cap Vial (810142C-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


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Qingqing Lin et al.
Biophysical journal, 105(12), 2733-2742 (2013-12-24)
Because transmembrane (TM) protein localization, or nonlocalization, in ordered membrane domains (rafts) is a key to understanding membrane domain function, it is important to define the origin of protein-raft interaction. One hypothesis is that a tight noncovalent attachment of TM
Transmembrane Protein (Perfringolysin O) Association with Ordered Membrane Domains (Rafts) Depends Upon the Raft-Associating Properties of Protein-Bound Sterol
Lin Q and LondonE
Biophysical Journal, 105(12), 2733-2742 (2013)
Qingqing Lin et al.
The Journal of biological chemistry, 288(2), 1340-1352 (2012-11-15)
The hypothesis that mismatch between transmembrane (TM) length and bilayer width controls TM protein affinity for ordered lipid domains (rafts) was tested using perfringolysin O (PFO), a pore-forming cholesterol-dependent cytolysin. PFO forms a multimeric barrel with many TM segments. The
Peter J Quinn
Progress in lipid research, 49(4), 390-406 (2010-05-19)
Domains in cell membranes are created by lipid-lipid interactions and are referred to as membrane rafts. Reliable isolation methods have been developed which have shown that rafts from the same membranes have different proteins and can be sub-fractionated by immunoaffinity

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