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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (810110P-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand 810110P
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31)
InChI 密鑰
SAAVELCIPHKGJE-UHFFFAOYSA-N
一般說明
12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe and is a long-chain fatty acid (LCFA) derivative.
應用
12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay. It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).
生化／生理作用
12-NBD Stearate incorporated in lipid droplets and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport. The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake and inhibited by filipin III.
包裝
5 mL Amber Glass Screw Cap Vial (810110P-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Targeting fatty acid binding protein (FABP) anandamide transporters-a novel strategy for development of anti-inflammatory and anti-nociceptive drugs
Berger WT, et al.
PLoS ONE, 7(12) (2012)
Lu Bai et al.
ACS infectious diseases, 6(4), 637-648 (2020-02-14)
Assembly of the bacterial cell wall requires not only the biosynthesis of cell wall components but also the transport of these metabolites to the cell exterior for assembly into polymers and membranes required for bacterial viability and virulence. LprG is
Tracking of drug release and material fate for naturally derived omega-3 fatty acid biomaterials
Faucher KM, et al.
Annals of Biomedical Engineering, 44(3), 782-792 (2016)
B P Atshaves et al.
The American journal of physiology, 274(3 Pt 1), C633-C644 (1998-04-08)
The effect of cellular differentiation on fatty acid uptake and intracellular diffusion was examined in transfected pluripotent mouse embryonic stem (ES) cells stably expressing intestinal fatty acid binding protein (I-FABP). Control ES cells, whether differentiated or undifferentiated, did not express
Gregory Carbonetti et al.
Scientific reports, 9(1), 18944-18944 (2019-12-14)
Prostate cancer (PCa) is defined by dysregulated lipid signaling and is characterized by upregulation of lipid metabolism-related genes including fatty acid binding protein 5 (FABP5), fatty acid synthase (FASN), and monoacylglycerol lipase (MAGL). FASN and MAGL are enzymes that generate
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