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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 5 mg (700066P-5mg)
製造商／商標名
Avanti Research™ - A Croda Brand 700066P
運輸包裝
dry ice
儲存溫度
−70°C
SMILES 字串
OC1CCC2(C3CCC4(C(CCC4C(CCCC(C)C)C)C3=CC=C2C1)C)C
InChI
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3
InChI 密鑰
UCTLRSWJYQTBFZ-UHFFFAOYSA-N
一般說明
7-脱氢胆固醇是胆固醇合成中产生的代谢物。它是一种主要存在于表皮中的不饱和甾醇。
應用
7-脱氢胆固醇已被用于：
- 在基于气相色谱/质谱（GC/MS）的甾醇分析中，定量少突胶质前体细胞（OPCs）中的7-脱氢胆固醇
- 作为内标物，用于使用超高效液相色谱-串联质谱（UHPLC-MS/MS）分析甾醇和羟固醇
- 作为内标物，用于通过液相(LC)-MS法测量脂质
生化／生理作用
7-脱氢胆固醇在高温和紫外线条件下作为维生素D3的前体。
包裝
5 mL琥珀色玻璃螺旋盖样品瓶（700066P-5mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Biosynthesis of Vitamin D in Skin
Principles of Medical Biology (1997)
Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP
Allimuthu D, et al.
Cell Chemical Biology, 26(4), 593-599 (2019)
Metabolic Precursor of Cholesterol Causes Formation of Chained Aggregates of Liquid-Ordered Domains.
Galya Staneva et al.
Langmuir : the ACS journal of surfaces and colloids, 32(6), 1591-1600 (2016-01-20)
7-Dehydrocholesterol, an immediate metabolic predecessor of cholesterol, can accumulate in tissues due to some metabolic abnormalities, causing an array of symptoms known as Smith-Lemli-Opitz syndrome. Enrichment of cellular membranes with 7-dehydrocholesterol interferes with normal cell-signaling processes, which involve interaction between
Josi Herron et al.
Current protocols in toxicology, 78(1), e65-e65 (2018-10-16)
Cholesterol and cholesterol-derived oxysterols are critical for embryonic development, synapse formation and function, and myelination, among other biological functions. Indeed, alterations in levels of cholesterol, sterol precursors, and oxysterols result in a variety of developmental disorders, emphasizing the importance of
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