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Merck

700048P

Avanti

24(R/S),25-epoxycholesterol-d6

Avanti Research - A Croda Brand

别名:

26,26,26,27,27,27-hexadeutero-24,25-epoxycholesterol

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About This Item

经验公式(希尔记法):
C27H38O2D6
分子量:
406.67
分類程式碼代碼:
41116107
NACRES:
NA.25

描述

24(R/S),25-epoxycholesterol-d6

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (700048P-1mg)

製造商/商標名

Avanti Research - A Croda Brand

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

24(R/S),25-epoxycholesterol-d6 is a deuterated side-chain substituted oxysterol.

應用

24(R/S),25-epoxycholesterol-d6 has been used as a primary and deuterated surrogate sterol standard in the quantitative analysis of extracted sterol samples from cultured cells and tissues.

生化/生理作用

24(S),25-epoxycholesterol maintains cholesterol homeostasis. It modulates hepatic cholesterol metabolism in vivo. 24(S),25-epoxycholesterol is synthesized in the mevalonate pathway. It inhibits sterol regulatory element-binding protein (SREBP) activation.
Deuterated sterol plays a vital role in chemical and biochemical research. It is used as a mechanistic tracer to study the role of steroid hormones in the function and modulation of several physiological processes. Deuterated sterol is also used as reference standards for mass spectrometry. 24(R/S),25-epoxycholesterol-d6 is a deuterium labeled sterol.

包裝

5 mL Amber Glass Screw Cap Vial (700048P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


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24 (S), 25-epoxycholesterol: a messenger for cholesterol homeostasis
Brown AJ
The International Journal of Biochemistry & Cell Biology, 41(4), 744-747 (2019)
Site-specific synthesis and application of Deuterium-Labeled sterols
Muchalski H, et al.
Archive for Organic Chemistry (2017)
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry
McDonald J, et al.
Test, 432, 145-170 (2007)

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