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Merck

700034P

Avanti

7α-羟基胆固醇

Avanti Research - A Croda Brand

别名:

胆甾-5-烯-3b,7a-二醇;110808

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About This Item

经验公式(希尔记法):
C27H46O2
CAS号:
分子量:
402.65
分類程式碼代碼:
12352211
NACRES:
NA.25

描述

cholest-5-en-3β,7α-diol

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (700034P-10mg)
pkg of 1 × 5 mg (700034P-5mg)
pkg of 1 × 50 mg (700034P-50mg)

製造商/商標名

Avanti Research - A Croda Brand

運輸包裝

dry ice

儲存溫度

−20°C

InChI

1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1

InChI 密鑰

OYXZMSRRJOYLLO-RVOWOUOISA-N

一般說明

7a-羟基-胆固醇是一种B环取代的氧甾醇。

應用


  • Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.: This research investigated the relationship between bile acid metabolism and dementia through a comprehensive approach integrating metabolomics, transcriptomics, and pharmacoepidemiology. The findings suggest that alterations in bile acid synthesis may be linked to the pathogenesis of dementia (Varma et al., 2021).

包裝

5 mL琥珀色玻璃螺旋盖小瓶(700034P-10mg)
5 mL琥珀色玻璃螺旋盖小瓶(700034P-50mg)
5 mL琥珀色玻璃螺旋盖小瓶(700034P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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访问文档库

Mustafa Yalcinkaya et al.
Journal of lipid research (2020-01-08)
Loss of pancreatic β-cell mass and function as a result of sustained endoplasmic reticulum (ER) stress is a core step in the pathogenesis of diabetes mellitus type 2. The complex control of β-cells and insulin production involves hedgehog signaling pathways
Michael E Abrams et al.
Nature microbiology, 5(7), 929-942 (2020-04-15)
Cholesterol 25-hydroxylase (CH25H) is an interferon-stimulated gene that converts cholesterol to the oxysterol 25-hydroxycholesterol (25HC). Circulating 25HC modulates essential immunological processes including antiviral immunity, inflammasome activation and antibody class switching; and dysregulation of CH25H may contribute to chronic inflammatory disease

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