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Merck

W224820

Sigma-Aldrich

4-萜烯醇

greener alternative

natural, ≥95%, FG

别名:

4-萜烯醇, 4-松油烯醇

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About This Item

经验公式(希尔记法):
C10H18O
CAS号:
分子量:
154.25
FEMA號碼:
2248
EC號碼:
歐洲委員會號碼:
2229c
MDL號碼:
分類程式碼代碼:
12164502
PubChem物質ID:
Flavis號碼:
2.072
NACRES:
NA.21
感官的:
herbaceous; woody; pepper
等級:
FG
Fragrance grade
Halal
Kosher
natural
agency:
follows IFRA guidelines
食物過敏原:
no known allergens

等級

FG
Fragrance grade
Halal
Kosher
natural

品質等級

agency

follows IFRA guidelines

法律遵循

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117

化驗

≥95%

光學活性

[α]20/D −27°, neat

環保替代產品特色

Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

折射率

n20/D 1.478

bp

88-90 °C

密度

0.931 g/mL at 25

應用

flavors and fragrances

文件

see Safety & Documentation for available documents

食物過敏原

no known allergens

香料過敏原

no known allergens

環保替代類別

感官的

herbaceous; woody; pepper

SMILES 字串

CC(C)C1(O)CCC(C)=CC1

InChI

1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3

InChI 密鑰

WRYLYDPHFGVWKC-UHFFFAOYSA-N

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一般說明

天然存在:茴芹、罗勒、黑加仑、可可、芫荽、越橘、葡萄柚、柠檬、青柠檬、墨角兰、薄荷油、肉豆蔻和绿薄荷。

應用


  • Quantification of six volatile oil constituents of Oleum Cinnamomi in rat plasma and multiple tissues using GC-MS and its application to pharmacokinetic and tissue distribution studies.: This study by Chi MY et al. focused on quantifying volatile oil constituents, including 4-Carvomenthenol, in rat plasma and tissues using GC-MS, providing insights into their pharmacokinetics and tissue distribution (Chi et al., 2023).

  • 4-Carvomenthenol ameliorates the murine combined allergic rhinitis and asthma syndrome by inhibiting IL-13 and mucus production via p38MAPK/NF-κB signaling pathway axis.: This research by Bezerra Barros GC et al. demonstrated the anti-inflammatory effects of 4-Carvomenthenol in a murine model of allergic rhinitis and asthma, highlighting its potential therapeutic applications (Bezerra Barros et al., 2020).

  • Fragrance material review on 4-carvomenthenol.: Bhatia SP et al. reviewed the use of 4-Carvomenthenol as a fragrance material, discussing its chemical properties, safety, and applications in the fragrance industry (Bhatia et al., 2008).

生化/生理作用

30ppm 时的味道

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

174.2 °F - closed cup

閃點(°C)

79 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

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Antonella Casiraghi et al.
Pharmaceutical development and technology, 15(5), 545-552 (2009-10-22)
This work aimed to evaluate the effect induced by excipients conventionally used for topical dosage forms, namely isopropyl myristate (IPM) or oleic acid (OA) or polyethylene glycol 400 (PEG400) or Transcutol (TR), on the human skin permeability of terpinen-4-ol (T4OL)
Risa Haigou et al.
Journal of oleo science, 61(1), 35-43 (2011-12-23)
We examined the in vitro metabolism of (+)-terpinen-4-ol by human liver microsomes and recombinant enzymes. The biotransformation of (+)-terpinen-4-ol was investigated by gas chromatography-mass spectrometry (GC-MS). (+)-Terpinen-4-ol was found to be oxidized to (+)-(1R,2S,4S)-1,2-epoxy-p-menthan-4-ol, (+)-(1S,2R,4S)-1,2-epoxy-p-menthan-4-ol, and (4S)-p-menth-1-en-4,8-diol by human liver
Mi-Jin Park et al.
Journal of microbiology (Seoul, Korea), 48(4), 496-501 (2010-08-28)
In this study, the antibacterial activity of essential oil from Chamaecyparis obtusa (Sieb. et Zucc) leaves and twigs was investigated. The test strains were Klebsiella pneumoniae, Listeria monocytogenes, Salmonella typhimurium, Staphylococcus aureus, Escherichia coli, Legionella pneumophila, and Methicilline-resistant Staphylococcus aureus.
C Njume et al.
International journal of antimicrobial agents, 38(4), 319-324 (2011-07-15)
The aim of this study was to isolate and identify phytochemicals with anti-Helicobacter pylori activity from the stem bark of Sclerocarya birrea. The plant crude extract was fractionated by silica gel column and thin layer chromatography techniques, initially with ethyl
Kotchaphan Chooluck et al.
Planta medica, 78(16), 1761-1766 (2012-10-03)
The purpose of this study was to investigate dermal pharmacokinetics of terpinen-4-ol in rats following topical administration of plai oil derived from the rhizomes of Zingiber cassumunar Roxb. Unbound terpinen-4-ol concentrations in dermal tissue were measured by microdialysis. The dermal

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