所有图片(3)
About This Item
经验公式（希尔记法）:
C4H7NO2S
CAS号:
分子量:
133.17
Beilstein:
81065
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.22
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化驗
98%
形狀
powder
光學活性
[α]20/D −141°, c = 1.3 in H2O
反應適用性
reaction type: solution phase peptide synthesis
顏色
white
mp
190-200 °C (dec.) (lit.)
SMILES 字串
OC(=O)[C@@H]1CSCN1
InChI
1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1
InChI 密鑰
DZLNHFMRPBPULJ-VKHMYHEASA-N
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應用
用于肽偶联反应。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Bioorganic & Medicinal Chemistry Letters, 4, 887-887 (1994)
Florine Cavelier et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(10), 621-625 (2006-06-21)
As proline plays an important role in biologically active peptides, many analogues of this residue have been developed to modulate the proportion of cis and trans conformers. A correlation between the pyrrolidine ring shape and structural properties of proline has
Anahí Magdaleno et al.
PloS one, 4(2), e4534-e4534 (2009-02-21)
It is well established that L-proline has several roles in the biology of trypanosomatids. In Trypanosoma cruzi, the etiological agent of Chagas' disease, this amino acid is involved in energy metabolism, differentiation processes and resistance to osmotic stress. In this
Khalid Mohammed Khan et al.
Molecular diversity, 10(2), 223-231 (2006-05-20)
By using internal combinatorial library we were able to identify (4R)-thiazolidines carboxylic acid and its 2-substituted analogs as active inhibitors of urease. Molecular modeling and virtual screening were utilized to find out potential compounds. Computational techniques were employed at database
Rajani Korukonda et al.
Journal of medicinal chemistry, 49(17), 5282-5290 (2006-08-18)
Calpain is a cytosolic cysteine endopeptidase that has been implicated in a number of disorders including cancer. We have synthesized and studied the mu-calpain inhibitory activity and cytotoxicity of peptidyl aldehydes and peptidyl alpha-ketoamides with N-substituted D-proline or L-thiaproline residues
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