QBD10247

Thiol-dPEG^®₄-acid

>95% (HPLC)

• 别名: Carboxy-PEG₄-thiol, HS-PEG₄-COOH, Thiol-PEG-acid, Thiol-PEG₄-COOH, Thiol-PEG₄-acid
• 经验公式（希尔记法）: C₁₁H₂₂O₆S
• 分子量: 282.35
• MDL號碼: MFCD11041132
• 分類程式碼代碼: 12352106
• NACRES: NA.22

属性

• 化驗: >95% (HPLC)
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: Pegylations
• 聚合物結構: shape: linear; functionality: heterobifunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: SCCOCCOCCOCCOCCC(=O)O
• InChI: 1S/C11H22O6S/c12-11(13)1-2-14-3-4-15-5-6-16-7-8-17-9-10-18/h18H,1-10H2,(H,12,13)
• InChI 密鑰: ORLGUGSEJFKLED-UHFFFAOYSA-N

说明

特點和優勢

Thiol-dPEG₄-acid is a sulfhydryl-containing, crosslinking PEGylation reagent that has a cross-bridge of monodisperse polyethylene glycol. The single molecular weight, discrete-length PEG (dPEG) chain is 16 atoms (18.3 Å) long. The sulfhydryl end of the crosslinker reacts with gold (forming dative bonds) and with thiol-reactive functional groups such as maleimide, bromoacetyl, SPDP, and thiol. The carboxylic acid end of the molecule couples to free amines using EDC or any suitable carbodiimide. An acylating agent such as N-hydroxysuccinimide (NHS) or 2,3,5,6-tetrafluorophenol (TFP) can enhance coupling efficiency. The carboxylate must react after the sulfhydryl conjugation.

法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable