D178454

亚磷酸二甲酯

98%

• 别名: Dimethoxyphosphine oxide, Dimethyl hydrogen phosphite, Dimethyl hydrogen phosphonate, Dimethyl phosphonate, Hydrogen dimethyl phosphite
• 线性分子式: (CH₃O)₂P(O)H
• CAS号: 868-85-9
• 分子量: 110.05
• Beilstein: 1697490
• EC號碼: 212-783-8
• MDL號碼: MFCD00044633
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24893543
• NACRES: NA.22

属性

• 品質等級: 200
• 化驗: 98%
• 形狀: liquid
• 雜質: ≤0.5% trimethyl phosphate; ≤1% methyl alcohol
• 折射率: n20/D 1.402 (lit.)
• bp: 170-171 °C (lit.)
• 密度: 1.2 g/mL at 25 °C (lit.)
• SMILES 字串: [H]P(=O)(OC)OC
• InChI: 1S/C2H7O3P/c1-4-6(3)5-2/h6H,1-2H3
• InChI 密鑰: HZCDANOFLILNSA-UHFFFAOYSA-N

说明

應用

Dimethyl phosphite is used in the synthesis of α-aminophosphonates, which are medicinally important phosphorus analogs of amino acids, by treating with an amine and an aldehyde or a ketone. It can also be employed in asymmetric hydrophosphonylation of aldehydes to synthesize optically active α-hydroxy phosphonates.

Dimethyl phosphite may be used as an effective alternative to organic tin hydrides as radical reducing agents for organic halides, thionoesters, and isocyanides to form the corresponding hydrocarbons. Radical translocation/cyclization reactions of terminal alkynes to form cyclic phosphonates can also be effectively carried using dimethyl phosphite as a reagent under tin-free condition.

安全信息

• 象形圖: GHS08,GHS07
• 訊號詞: Warning
• 危險聲明: H317,H341,H351,H412
• 防範說明: P202 - P261 - P273 - P280 - P302 + P352 - P308 + P313
• 危險分類: Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Skin Sens. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 158.0 °F - closed cup
• 閃點（°C）: 70 °C - closed cup
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter