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Merck
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Key Documents

CDP-507

Sigma-Aldrich

Cationic Liposomes

DOTAP-based - DOTAP:DOPC (2:98 molar ratio 10mM)

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About This Item

分類程式碼代碼:
12352211
NACRES:
NA.25

品質等級

成份

Phosphate buffered saline

濃度

10 mM

雜質

2 mol % DOTAP
98 mol % DOPC

粒徑

100 nm

pH值

7.4

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一般說明

Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. One of the parameters that affects this interaction is the charge of the liposomal membrane. DOTAP is a positively charged molecule that is combined with DOPC as a matrix lipid. Various amounts of cationic DOTAP from 0.5% to 50% results in liposomes with various zeta potentials. Charged liposomes, such as the cationic DOTAP-based liposomes, can be used in various in vitro studies and drug delivery applications. The cationic DOTAP-based liposomes have varying degrees of postive charge and can be used to study the interaction of these liposomes with various types of enzymes, proteins, peptides and other moelcules that interact with the surface of liposomes.

應用

Drug delivery
Lipid-protein interactions

儲存和穩定性

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

法律資訊

Cellsome is a trademark of Encapsula NanoSciences
Product of Encapsula Nanosciences

免責聲明

For research use only

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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