形狀
powder
品質等級
反應適用性
reagent type: linker
官能基
Boc
carboxylic acid
儲存溫度
2-8°C
SMILES 字串
CC(C)(OC(N1CC(C2=CN=C(C(O)=O)C=N2)C1)=O)C
應用
5-(1-(tert-Butoxycarbonyl)azetidin-3-yl)pyrazine-2-carboxylic acid is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. Developed in partnership with ComInnex.
Similar linkers in this series:
920487
920495
920576
ADV638390284
Similar linkers in this series:
920487
920495
920576
ADV638390284
其他說明
法律資訊
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
相關產品
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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