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Merck

911569

Sigma-Aldrich

Polyester bis-MPA dendron

no. Surface Groups 4, NHBoc, 1 Biotin (core), generation 2

别名:

Biotin-NHBoc dendron, Bis-MPA dendron

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About This Item

经验公式(希尔记法):
C65H108N6O28S
分子量:
1453.64
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

solid (Viscous)

分子量

generation 2

號表面基團

4

顏色

colorless to white

儲存溫度

−20°C

一般說明

  • Polymer architecture: Dendron
  • Generation: 2
  • Core functional group: Biotin
  • End Group Functionality: NHBoc
  • No. Surface Groups: 4
  • Calculated Mol. Wt.: 1453.7 g/mol
  • bis-MPA = 2,2-bis(hydroxymethyl)propionic acid

應用

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications.The NHBoc-functionalized corona and Biotin-functionalized core of this product can be readily used in bioconjugation reactions.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

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