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Merck

910015

Sigma-Aldrich

17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid

≥95%

别名:

Azido-PEG5-CH2CO2H, Azido-PEG5-acid, N3-PEG5-CH2COOH

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About This Item

经验公式(希尔记法):
C12H23N3O7
分子量:
321.33
MDL號碼:
分類程式碼代碼:
12352106

化驗

≥95%

形狀

(Liquid or Semi-solid or Paste or Solid)

反應適用性

reaction type: click chemistry
reagent type: cross-linking reagent

官能基

azide
carboxylic acid

儲存溫度

2-8°C

SMILES 字串

OC(COCCOCCOCCOCCOCCN=[N+]=[N-])=O

應用

This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG5-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

法律資訊

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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