903701

tBuDavePhos Pd G3

1:1 THF adduct

• 别名: t-BuDavePhos G3 Palladacycle, t-BuDavePhos Palladacycle
• 线性分子式: C₃₅H₄₅N₂O₃PPdS · C₄H₈O
• 分類程式碼代碼: 12161600
• NACRES: NA.22

属性

• 形狀: powder or crystals
• 特點: generation 3
• 反應適用性: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings
• 官能基: phosphine
• SMILES 字串: CN(C1=C(C2=C(P(C(C)(C)C)C(C)(C)C)C=CC=C2)C=CC=C1)C.NC3=C(C4=C([Pd]OS(C)(=O)=O)C=CC=C4)C=CC=C3.C5COCC5
• InChI: 1S/C22H32NP.C12H10N.C4H8O.CH4O3S.Pd/c1-21(2,3)24(22(4,5)6)20-16-12-10-14-18(20)17-13-9-11-15-19(17)23(7)8;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-2-4-5-3-1;1-5(2,3)4;/h9-16H,1-8H3;1-6,8-9H,13H2;1-4H2;1H3,(H,2,3,4);/q;;;;+1/p-1
• InChI 密鑰: PJRGOORCHKDNHB-UHFFFAOYSA-M

说明

一般說明

tBuDavePhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has a long life in solutions. tBuDavePhos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

應用

tBuDavePhos Pd G3 has been used as a precatalyst for the Synthesis of Aryl Sulfonamides via Palladium-Catalyzed Chlorosulfonylation of Arylboronic Acids. It may also be used for a variety of C-C and C-N cross-coupling reactions.

其他說明

Technology Spotlight: G3 and G4 Buchwald Precatalysts

Synthesis of Aryl Sulfonamides via Palladium-Catalyzed Chlorosulfonylation of Arylboronic Acids

Design and preparation of new palladium precatalysts for C-C and C-N cross-coupling reactions

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable