900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 别名: Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• 经验公式（希尔记法）: C₁₁H₁₂BrFO₂SSi
• CAS号: 2088829-15-4
• 分子量: 335.26
• MDL號碼: MFCD31579818
• 分類程式碼代碼: 12352200
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder or crystals
• 反應適用性: reaction type: click chemistry
• 儲存溫度: −20°C
• SMILES 字串: [Si](C)(C)(C)C#Cc1cc(cc(c1)Br)[S](=O)(=O)F
• InChI: 1S/C11H12BrFO2SSi/c1-17(2,3)5-4-9-6-10(12)8-11(7-9)16(13,14)15/h6-8H,1-3H3
• InChI 密鑰: CUUVPHAGWQDSCZ-UHFFFAOYSA-N

说明

應用

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

其他說明

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable