804568

(R,S)-Bode Kinetic Resolution Catalyst

• 别名: (4aR,9aS)-6-Bromo-4-hydroxy-4,4a,9,9a-tetrahydroindeno[2,1-b][1,4]oxazin-3(2H)-one
• 经验公式（希尔记法）: C₁₁H₁₀BrNO₃
• CAS号: 1394957-71-1
• 分子量: 284.11
• MDL號碼: MFCD29037020
• 分類程式碼代碼: 12352101
• PubChem物質ID: 329768882
• NACRES: NA.22

属性

• 形狀: solution
• 品質等級: 100
• 官能基: bromo; ether
• 儲存溫度: 15-25°C
• SMILES 字串: O=C(CO1)N(O)[C@@]2([H])[C@]1([H])CC3=CC=C(Br)C=C32
• InChI: 1S/C11H10BrNO3/c12-7-2-1-6-3-9-11(8(6)4-7)13(15)10(14)5-16-9/h1-2,4,9,11,15H,3,5H2/t9-,11+/m0/s1
• InChI 密鑰: FQXSUQCCAHKURK-GXSJLCMTSA-N

说明

應用

The following hydroxamic acid catalyst was shown by Bode and coworkers to assist in the kinetic resolution of cyclic amines through acylation of one enantiomer, which can be controlled using either the (R or S)- or (S or R)-Bode Kinetic Resolution Catalyst, both of which are also available through Sigma-Aldrich.
It can also be employed in the preparation of nonracemic piperidines by kinetic resolution using an α-hydroxy-α′, β-unsaturated ketone in the presence of a pyrrolotriazolium salt.

其他說明

Expanded substrate scope and catalyst optimization for the catalytic kinetic resolution of N-heterocycles

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P301 + P312 + P330
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable