799580

HandaPhos

≥95%

• 别名: (2S,3S)-4-(2,6-Dimethoxyphenyl)-3-(2-methyl-2-propanyl)-2-(2,4,6-triisopropylbenzyl)-2,3-dihydro-1,3-benzoxaphosphole
• 经验公式（希尔记法）: C₃₅H₄₇O₃P
• CAS号: 1908442-13-6
• 分子量: 546.72
• 分類程式碼代碼: 12350000
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder
• 反應適用性: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• 環保替代產品特色: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• 官能基: phosphine
• 環保替代類別: Aligned,
• 儲存溫度: 2-8°C
• SMILES 字串: COC(C=CC=C1OC)=[C@]1[C@@]2=C([P@](C(C)(C)C)[C@@H](CC3=C(C(C)C)C=C(C(C)C)C=C3C(C)C)O4)C4=CC=C2
• InChI: 1S/C35H47O3P/c1-21(2)24-18-26(22(3)4)28(27(19-24)23(5)6)20-32-38-31-17-12-14-25(34(31)39(32)35(7,8)9)33-29(36-10)15-13-16-30(33)37-11/h12-19,21-23,32H,20H2,1-11H3/t32-,39?/m0/s1
• InChI 密鑰: RXGMKJPMNONITA-DKHGMYDOSA-N

说明

一般說明

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

應用

HandaPhos forms a 1:1 complex with Pd(OAc)₂ thereby arriving at a pre-catalyst, used at the ppm level, that enables Suzuki-Miyaura cross-couplings to be run under micellar catalysis in water at room temperature. To be used in tandem with Designer Surfactant TPGS-750-M.

其他說明

HandaPhos: A General Ligand Enabling Sustainable ppm Levels of Palladium-Catalyzed Cross-Couplings in Water at Room Temperature

Watch Professor Lipshutz talk about HandaPhos in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable