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Merck

79229

Sigma-Aldrich

N-Boc-1,6-己二胺

≥98.0% (NT)

别名:

N-(6-氨基己基)氨基甲酸叔丁酯, N-Boc-1,6-二氨基己烷

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About This Item

经验公式(希尔记法):
C11H24N2O2
CAS号:
分子量:
216.32
Beilstein:
2219107
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥98.0% (NT)

形狀

liquid

反應適用性

reagent type: cross-linking reagent

折射率

n20/D 1.462

密度

0.965 g/mL at 20 °C (lit.)

官能基

Boc
amine

SMILES 字串

NCCCCCCNC(OC(C)(C)C)=O

InChI

1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)

InChI 密鑰

RVZPDKXEHIRFPM-UHFFFAOYSA-N

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應用

N-Boc-1,6-己二胺在以下示例中,用作线性己基间隔基(C6-间隔基):
  • 合成用于基因递送的可生物降解的聚二硫胺。
  • 构建治疗诊断学的多功能树枝状聚合物。
  • 合成聚酰胺铂抗癌复合物,专用于靶向肿瘤特异性DNA序列。
  • 制备抗蛋白吸附的自组装单分子膜(SAM)。
  • [N-(6-(4-羟基-6-异丙氨基-1,3,5-三嗪-2-基氨基)基氨基)-5-羟基-1,4-萘醌-3-丙酰胺](JUG-HATZ)可用于电化学免疫传感器设计。
用于引入 C6 间隔臂的试剂。

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

257.0 °F - closed cup

閃點(°C)

125 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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A label-free electrochemical immunosensor for direct, signal-on and sensitive pesticide detection.
Tran HV, et al.
Biosensors And Bioelectronics, 31(1), 62-68 (2012)
Haonan Xing et al.
Colloids and surfaces. B, Biointerfaces, 182, 110355-110355 (2019-07-16)
Inspired by the excellent membrane affinity of antimicrobial polymers, we synthesized a novel biodegradable poly(amino amine) polymer with pendent side chains that mimic the widely used biocide polyhexamethylene biguanide (PHMB) for gene delivery. Michael addition polymerization was utilized to form
Construction of a well-defined multifunctional dendrimer for theranostics.
Ornelas C, et al.
Organic Letters, 13(5), 976-979 (2011)
Yan Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 328, 970-984 (2020-09-15)
To avoid poly(ethylene glycol)-related issues of nanomedicines such as accelerated blood clearance, fully N-2-hydroxypropyl methacrylamide (HPMAm)-based polymeric micelles decorated with biotin for drug delivery were designed. To this end, a biotin-functionalized chain transfer agent (CTA), 4-cyano-4-[(dodecylsulfanylthiocarbonyl)-sulfanyl]pentanoic acid (biotin-CDTPA), was synthesized
Preparation of mixed self-assembled monolayers (SAMs) that resist adsorption of proteins using the reaction of amines with a SAM that presents interchain carboxylic anhydride groups.
Chapman R G, et al.
Langmuir, 16(17), 6927-6936 (2000)

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