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纳米非晶胶体 SiO 2 颗粒的组成
分散负荷和介质 (27±3) wt.-% 水溶液
粒径 d90(体积分布;DLS)< 50 nm
pH 2 ± 1
密度 (1.2±0.1) g/l
一级粒度 < 20 nm
三乙氧基丙基氨基硅烷表面改性
分散负荷和介质 (27±3) wt.-% 水溶液
粒径 d90(体积分布;DLS)< 50 nm
pH 2 ± 1
密度 (1.2±0.1) g/l
一级粒度 < 20 nm
三乙氧基丙基氨基硅烷表面改性
應用
二氧化硅纳米颗粒在包括骨工程 和药物输送 在内的生物技术中起着至关重要的作用。这些材料表面存在的氨基官能团为进一步修饰和共轭目标部分提供了合成手柄 。氨基功能化硅胶颗粒可用于体内基因传递 、纳米复合物形成 和生物膜形成 。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
儲存類別代碼
8B - Non-combustible corrosive hazardous materials
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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Proceedings of the National Academy of Sciences of the United States of America, 102(2), 279-284 (2005-01-05)
This article reports a multidisciplinary approach to produce fluorescently labeled organically modified silica nanoparticles as a nonviral vector for gene delivery and biophotonics methods to optically monitor intracellular trafficking and gene transfection. Highly monodispersed, stable aqueous suspensions of organically modified
Physical chemistry chemical physics : PCCP, 15(27), 11454-11460 (2013-06-12)
We investigated the drug releasing behavior of a novel nanocarrier system, utilizing a peptide to act as a nanogate to the mesopore, on a mesoporous silica nanoparticle. The surface peptide on mesoporous silica displayed pH-dependant mesopore cap-uncap switching behavior, enabled
Proceedings of the National Academy of Sciences of the United States of America, 102(32), 11539-11544 (2005-07-30)
This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as a nonviral vector for efficient in vivo gene delivery. Highly monodispersed, stable aqueous suspension of nanoparticles, surface-functionalized with amino groups for binding of DNA, were prepared and
Langmuir : the ACS journal of surfaces and colloids, 20(3), 722-729 (2005-03-19)
Heme protein hemoglobin (Hb) or myoglobin (Mb) and silica nanoparticles in a variety of charge states were assembled layer-by-layer into films on solid surfaces to investigate the driving forces for film assembly. Cyclic voltammetry (CV), quartz crystal microbalance (QCM), X-ray
Preparation and characterization of epoxy composites filled with functionalized nanosilica particles obtained via sol-gel process
Polymer, 42(3), 879-887 (2000)
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