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化驗
95%
形狀
solid
反應適用性
reaction type: click chemistry
reagent type: linker
mp
206-225 °C (decomposition)
官能基
amine
儲存溫度
−20°C
SMILES 字串
NCC1=CC=C(C2=NN=CN=N2)C=C1.[H]Cl
InChI
1S/C9H9N5.ClH/c10-5-7-1-3-8(4-2-7)9-13-11-6-12-14-9;/h1-4,6H,5,10H2;1H
InChI 密鑰
FAAUXGMWUKVOPI-UHFFFAOYSA-N
一般說明
4-(1,2,4,5-四嗪-3-基)苯基)甲胺是一种1,2,4,5-四嗪衍生物,能够与张力较大的烯烃发生[4+2] Diels-Alder环加成反应,这使其在生物正交标记和细胞检测应用中非常实用。
應用
胺官能化四嗪可用于反电子需求Diels-Alder环加成反应。四嗪将与张力较大的烯烃反应,如反式环辛烯、降冰片烯和环丙烯,产生稳定的共价键。已证明四嗪可用于许多生物成像和生物共轭应用的生物正交反应。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
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Journal of Medicinal Chemistry, 59(20), 9381-9389 (2016)
Bioconjugate chemistry, 22(11), 2263-2270 (2011-09-29)
1,2,4,5-Tetrazines have been established as effective dienes for inverse electron demand [4 + 2] Diels-Alder cycloaddition reactions with strained alkenes for over 50 years. Recently, this reaction pair combination has been applied to bioorthogonal labeling and cell detection applications; however
Bioconjugate chemistry, 19(12), 2297-2299 (2008-12-05)
Bioorthogonal tetrazine cycloadditions have been applied to live cell labeling. Tetrazines react irreversibly with the strained dienophile norbornene forming dihydropyrazine products and dinitrogen. The reaction is high yielding, selective, and fast in aqueous media. Her2/neu receptors on live human breast
实验方案
Protocol for GC Analysis of Bacterial Acid Methyl Esters (BAMEs) on Equity®-1
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