706531

N-Boc-1,2,3,6-四氢吡啶-4-硼酸频哪醇酯

95%

• 别名: (N-叔丁氧羰基)-1,2,3,6-四氢吡啶-4-硼酸频哪醇酯
• 经验公式（希尔记法）: C₁₆H₂₈BNO₄
• CAS号: 286961-14-6
• 分子量: 309.21
• MDL號碼: MFCD03840345
• 分類程式碼代碼: 12352103
• PubChem物質ID: 329762650
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: 95%
• 形狀: powder
• mp: 100-114 °C
• SMILES 字串: CC(C)(C)OC(=O)N1CCC(=CC1)B2OC(C)(C)C(C)(C)O2
• InChI: 1S/C16H28BNO4/c1-14(2,3)20-13(19)18-10-8-12(9-11-18)17-21-15(4,5)16(6,7)22-17/h8H,9-11H2,1-7H3
• InChI 密鑰: VVDCRJGWILREQH-UHFFFAOYSA-N

说明

一般說明

Boc-THP-Bpin is frequently used in metal catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings.

應用

Reagent used for

• Suzuki-Miyaura cross-coupling using palladium phosphine catalyst
• Palladium-catalyzed ligand-controlled regioselective Suzuki coupling
• Palladium-catalyzed Suzuki-Miyaura coupling
• Suzuki coupling followed by iodolactonization reaction
• Wrenchnolol derivative optimized for gene activation in cells

Reagent used in Preparation of several enzymatic inhibitors and receptor ligands

• Orally active anaplastic lymphoma kinase inhibitors
• Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes
• 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands
• Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder
• Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)