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702153

Sigma-Aldrich

羟基磷灰石

nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)

别名:

Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate

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About This Item

线性分子式:
[Ca5(OH)(PO4)3]x
CAS号:
12167-74-7
分子量:
502.31
MDL號碼:
MFCD00010904
分類程式碼代碼:
12352302
PubChem物質ID:
329762350
NACRES:
NA.23

形狀

dispersion
nanoparticles

品質等級

100

包含

≤0.025 wt. % dispersant (non-metal based)

濃度

10 wt. % in H2O

表面積

14.3 m2/g , typical

粒徑

<200 nm (BET)

pH值

4-6

密度

1.038 g/mL at 25 °C

SMILES 字串

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI 密鑰

XYJRXVWERLGGKC-UHFFFAOYSA-D

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相关类别

一般說明

羟基磷灰石(HAP)是一种骨传导生物陶瓷材料，它具有独特的性能可以直接与活体组织结合。它可以通过多种技术制备，如溶液-凝胶法、水热法、多重乳化法、仿生沉积法和电沉积法。

應用

羟基磷灰石可被用于：
  • 一种替代骨的植入材料，因为其化学成分与 骨中无机盐成分相似且有骨诱导特性。
  • 基因和药物载体，因为它具有封装能力和 对许多药物、蛋白有亲和力。
  • 对pH响应的微粒乳化剂。

特點和優勢

  • 生物相容的
  • 骨传导的
  • 在 胜利条件下稳定
  • 高机械强度高强度

法律資訊

Engi-Mat Co.产品。

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
MKCP8250
MKCN6392
MKCL6094
MKBW5896V
MKBR8934V

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Liam M Grover et al.
Biomaterials, 34(28), 6631-6637 (2013-06-12)
Pyrophosphate ions are both inhibitors of HA formation and substrates for phosphatase enzymes. Unlike polyphosphates their hydrolysis results simultaneously in the complete loss of mineral formation inhibition and a localised elevation in orthophosphate ion concentration. Despite recent advances in our
W Zhang et al.
Journal of dental research, 92(12), 1136-1141 (2013-10-08)
Stem cell-based bone tissue engineering has been recognized as a new strategy for maxillary sinus floor elevation. More rapid bone formation may enhance this technique when simultaneous dental implant placement is desired. Adipose tissue-derived stem cells (ADSCs) and bone marrow
Satyavrata Samavedi et al.
Acta biomaterialia, 9(9), 8037-8045 (2013-06-25)
Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the regeneration of bone tissue because of their ability to induce osteoblastic differentiation in progenitor cells. Despite the progress made towards fabricating CPCs possessing a range of surface features
Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
Thomas Lyon et al.
The Journal of bone and joint surgery. American volume, 95(23), 2088-2096 (2013-12-07)
Recombinant human bone morphogenetic protein-2 (rhBMP-2) applied on an absorbable collagen sponge improves open tibial fracture-healing as an adjunct to unreamed intramedullary nail fixation. We evaluated rhBMP-2 and a new, injectable calcium phosphate matrix (CPM) formulation in acute closed tibial
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