跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

653152

Sigma-Aldrich

4-巯基苯基乙酸

97%

别名:

2-（4-巯基苯基）乙酸, 4-巯基苯基乙酸, 对巯基苯乙酸, （4-巯基苯基）乙酸, （4-羧甲基）苯硫酚

登录查看公司和协议定价
所有图片(1)

About This Item

线性分子式:
HSC6H4CH2CO2H
CAS号:
39161-84-7
分子量:
168.21
MDL號碼:
MFCD00797617
分類程式碼代碼:
12352100
PubChem物質ID:
24883931
NACRES:
NA.22

化驗

97%

形狀

solid

mp

105-109 °C (lit.)

官能基

carboxylic acid

儲存溫度

2-8°C

SMILES 字串

OC(=O)Cc1ccc(S)cc1

InChI

1S/C8H8O2S/c9-8(10)5-6-1-3-7(11)4-2-6/h1-4,11H,5H2,(H,9,10)

InChI 密鑰

ORXSLDYRYTVAPC-UHFFFAOYSA-N

相关类别

一般說明

4-巯基苯基乙酸(MPAA)是一种硫醇添加剂，广泛应用于自然化学偶联（NCL）反应，用于肽片段的选择性高效偶联。

應用

4-巯基苯基乙酸用于通过序列自然化学连接由双（2-磺酰乙基）氨基肽制备小泛素修饰肽。
可用于：
  • 树脂制备肽-α噻吩基酯，以在化学连接过程中化学合成多肽。
  • 在一锅法中，采用天然化学连接和/或脱硫法去保护（乙酰胺基-甲基）半胱氨酸来制备多肽。
  • 钯通过天然化学连接法促进N-端半胱氨酸去保护，以制备合成挑战性蛋白。

象形圖

CorrosionExclamation mark
GHS05,GHS07

訊號詞

Danger

危險聲明

H315,H318,H335

危險分類

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCQ8150
MKCM9940
MKCJ9065
MKCG4136
MKCF2365

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Sunithi Gunasekera et al.
Frontiers in microbiology, 11, 168-168 (2020-03-11)
Can antimicrobial activity and peptide stability of alpha-helical peptides be increased by making them into dimers and macrocycles? Here, we explore that concept by using KR-12 as the starting point for peptide engineering. KR-12 has previously been determined as the
Lin Zhang et al.
Chemical science, 10(11), 3271-3280 (2019-04-19)
Targeted antibody blocking enables characterization of binding sites on immunoglobulin G (IgG), and can efficiently eliminate harmful antibodies from organisms. In this report, we present a novel peptide-denoted as a dual-functional conjugate of antigenic peptide and Fc-III mimetics (DCAF)-for targeted
Palladium mediated rapid deprotection of N-terminal cysteine under native chemical ligation conditions for the efficient preparation of synthetically challenging proteins
Jbara M, et al.
Journal of the American Chemical Society, 138(15), 5069-5075 (2016)
One-pot chemical synthesis of small ubiquitin-like modifier protein-peptide conjugates using bis (2-sulfanylethyl) amido peptide latent thioester surrogates
Boll E, et al.
Nature Protocols, 10(2), 269-269 (2015)
Daniel J Capon et al.
Proceedings of the Japan Academy. Series B, Physical and biological sciences, 87(9), 603-616 (2011-11-15)
There is a significant need for antibodies that can bind targets with greater affinity. Here we describe a novel strategy employing chemical semisynthesis to produce symmetroadhesins: antibody-like molecules having nonprotein hinge regions that are more flexible and extendible and are
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门