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描述
C9H7NO · ½H2SO4 (Linear Formula)
化驗
≥98.0% (dry substance, T)
雜質
~5% water
顏色
yellow
抗生素活性譜
fungi
作用方式
DNA synthesis | interferes
enzyme | inhibits
SMILES 字串
OS(O)(=O)=O.Oc1cccc2cccnc12.Oc3cccc4cccnc34
InChI
1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)
InChI 密鑰
YYVFXSYQSOZCOQ-UHFFFAOYSA-N
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一般說明
化学结构：喹诺酮类
應用
8-羟基喹啉半硫酸盐 (8-OHQ) 可用于制备具有蛋白酶抑制活性的 Cu [8-OHQ] 2。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Kenyon G Daniel et al.
Biochemical pharmacology, 67(6), 1139-1151 (2004-03-10)
Here we report that organic copper complexes can potently and selectively inhibit the chymotrypsin-like activity of the proteasome in vitro and in vivo. Several copper compounds, such as NCI-109268 and bis-8-hydroxyquinoline copper(II) [Cu(8-OHQ)(2)], can inhibit the chymotrypsin-like activity of purified
Ping Nan et al.
Environmental toxicology and pharmacology, 35(3), 434-443 (2013-03-12)
This study was a preliminary step in evaluating the genotoxic effects of 8-hydroxylquinoline (8-HOQ) in loach (Misgurnus anguillicaudatus) using the micronucleus, comet and RAPD assays. In the micronucleus test and comet assay, the micronuclei rate (%) and three comet parameters
Bhimashankar Mitkari et al.
Experimental neurology, 239, 158-162 (2012-10-13)
Cell therapies from various sources have been under intense research in stroke. Efficient homing of the cells to the injured brain without complications is necessary to realize the therapeutic potential of cell therapy. Intra-arterial (IA) infusion of cells bypasses the
Wenqi Sun et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 106, 275-283 (2013-02-19)
The title molecule (E)-2-[2-(2,6-dichlorophenyl)ethenyl]-8-hydroxyquinoline (DPEQ) was synthesized and characterized by FT-IR, UV-vis, NMR spectroscopy. The molecular geometry, vibrational frequencies and gauge independent atomic orbital (GIAO) 1H and 13C NMR chemical shift values of the compound in the ground state have
Meng Zhang et al.
Inorganic chemistry, 51(21), 11315-11323 (2012-10-09)
An artificial peptide with three pendant hydroxyquinoline (hq) ligands on a palindromic backbone was designed and used to form multimetallic assemblies. Reaction of the tripeptide with zinc acetate led to a highly fluorescent tripeptide duplex with three Zn(II) coordinative cross-links.
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