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Sigma-Aldrich

香豆素 6

≥99%

别名:

3-(2'-苯并噻唑基)-7-二乙基氨基香豆素, 3-(2-Benzothiazolyl)-N,N-diethylumbelliferylamine

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About This Item

经验公式（希尔记法）:
C20H18N2O2S
CAS号:
38215-36-0
分子量:
350.43
Beilstein:
1085798
EC號碼:
253-830-2
MDL號碼:
MFCD00041869
分類程式碼代碼:
12352103
PubChem物質ID:
329758042
NACRES:
NA.23

化驗

≥99%

形狀

solid

mp

208-210 °C (lit.)

λmax

443 nm

螢光

λem 494 nm in THF
λem 505 nm in ethanol (Lasing peak 534 nm, lasing range 515 - 558 nm (DMSO), pump source XeCl (308 nm))

軌道能量

HOMO 5.4 eV 
LUMO 2.7 eV 

OLED器件效能

ITO/Alq3:Coumarin 6/Mg:Ag

  • Color: green
  • Max. EQE: 2.5 %

SMILES 字串

CCN(CC)c1ccc2C=C(C(=O)Oc2c1)c3nc4ccccc4s3

InChI

1S/C20H18N2O2S/c1-3-22(4-2)14-10-9-13-11-15(20(23)24-17(13)12-14)19-21-16-7-5-6-8-18(16)25-19/h5-12H,3-4H2,1-2H3

InChI 密鑰

VBVAVBCYMYWNOU-UHFFFAOYSA-N

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一般說明

据报道，香豆素6作为荧光光谱法的光生命期标准品，对于生命期实验是最稳定的。

應用

作为绿色掺杂剂的材料
它可用于校准光生命期造影显微镜系统。
激光染料

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Deborah D Soto-Ortega et al.
Bioorganic & medicinal chemistry, 19(8), 2596-2602 (2011-04-05)
Aggregation of the amyloid-β protein (Aβ) plays a pathogenic role in the progression of Alzheimer's disease, and small molecules that attenuate Aβ aggregation have been identified toward a therapeutic strategy that targets the disease's underlying cause. Compounds containing aromatic structures
Xin Guan et al.
Drug delivery, 23(9), 3307-3318 (2016-04-14)
Utilization of quercetin (QT) in clinics is limited by its instability and poor solubility. To overcome these disadvantages, we prepared QT as QT-loaded PLGA-TPGS nanoparticles (QPTN) and examined its properties and therapeutic efficacy for liver cancer. QT-loaded PLGA nanoparticles (QPN)
Monitoring protein interactions in living cells with fluorescence lifetime imaging microscopy
Sun Y, et al.
Methods in Enzymology null
Seokjoon Lee et al.
Bioorganic & medicinal chemistry letters, 16(17), 4596-4599 (2006-06-24)
A series of 7-diethylaminocoumarin compounds were synthesized and the cytotoxicities were tested against human umbilical vein endothelial cell (HUVEC) and some cancer cells. We found that the introduction of cyano groups at the 4-position will promote the bioactivity. In particular
Testing fluorescence lifetime standards using two-photon excitation and time-domain instrumentation: rhodamine B, coumarin 6 and lucifer yellow.
Kristoffersen AS,et al.
Journal of Fluorescence null
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