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品質等級
化驗
97%
mp
53-56 °C (lit.)
SMILES 字串
Clc1cccc(Cl)c1S(Cl)(=O)=O
InChI
1S/C6H3Cl3O2S/c7-4-2-1-3-5(8)6(4)12(9,10)11/h1-3H
InChI 密鑰
WGGKQIKICKLWGN-UHFFFAOYSA-N
一般說明
2,6-Dichlorobenzenesulfonyl chloride, also known as 2,6-dichlorophenylsulfonyl chloride, is an aryl sulfonyl chloride derivative.
應用
2,6-Dichlorobenzenesulfonyl chloride may be used as a starting material in the multi-step synthesis of sulfonamide-containing diarylsquaramide. It may also be used in the synthesis of cycloheptyl substituted 1,2,4-triazolopyridine (TZP) analogs.
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Bioorganic & medicinal chemistry letters, 21(14), 4146-4149 (2011-06-22)
A series of pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 were modified to incorporate a novel 1,2,4-triazolopyridine scaffold. Optimization of substituents at the 3 and 8 position of the TZP core, with a special focus on enhancing metabolic stability, resulted in the
Bioorganic & medicinal chemistry letters, 17(6), 1713-1717 (2007-01-24)
N,N'-diarylsquaramides were prepared and evaluated as antagonists of CXCR2. The compounds were found to be potent and selective antagonists of CXCR2. Significant differences in SAR was observed relative to the previously described N,N'-diarylurea series. As was the case in the
商品
Aryl sulfonyl chloride derivatives are frequently used in parallel synthesis to synthesize sulfonamides and sulfonate linkages.
Aryl sulfonyl chloride derivatives are frequently used in parallel synthesis to synthesize sulfonamides and sulfonate linkages.
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