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品質等級
化驗
96%
光學活性
[α]20/D +16.5°, neat
光學純度
ee: 98% (GLC)
折射率
n20/D 1.432 (lit.)
bp
186-188 °C/765 mmHg (lit.)
密度
1.036 g/mL at 20 °C (lit.)
官能基
hydroxyl
SMILES 字串
C[C@H](O)CO
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3/t3-/m0/s1
InChI 密鑰
DNIAPMSPPWPWGF-VKHMYHEASA-N
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應用
(S)-(+)-1,2-丙二醇可用作合成以下物质的反应物:
- 在二甲基氨基吡啶(DMAP)催化剂存在的情况下以介晶羧酸通过酯化反应制备的光活性手性( S)-1, 2-丙二醇衍生物。
- 通过Mitsunobu 反应制备的3,4-乙烯二氧噻吩。
- 在高碘酸钠和氯化钌催化剂存在的情况下制备的邻二醇环硫酸酯。
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
217.4 °F - closed cup
閃點(°C)
103 °C - closed cup
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To determine whether the administration of mitomycin C prevents propylene glycol exposure from inducing middle-ear cholesteatoma and otitis media, in a rat model. Twenty-four Wistar rats underwent intratympanic injections on days 1, 8 and 15, via the tympanic membrane pars
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Glycol ethers are a class of semi-volatile substances used as solvents in a variety of consumer products like cleaning agents, paints, cosmetics as well as chemical intermediates. We determined 11 metabolites of ethylene and propylene glycol ethers in 44 urine
Cancer letters, 330(1), 74-83 (2012-11-29)
Multidrug resistance (MDR) is one of the major reasons for the failure of cancer chemotherapy. A newly reported liposome carrier, propylene glycol liposomes (EPI-PG-liposomes) were made to load epirubicin (EPI) which enhanced EPI absorption in MDR tumor cells to overcome
International journal of pharmaceutics, 443(1-2), 128-136 (2013-01-10)
Diclofenac-loaded phospholipid vesicles, namely conventional liposomes, ethosomes and PEVs (penetration enhancer-containing vesicles) were developed and their efficacy in TPA (phorbol ester) induced skin inflammation was examined. Vesicles were made from a cheap and unpurified mixture of phospholipids and diclofenac sodium;
Journal of cosmetic science, 64(3), 181-192 (2013-06-12)
It would be useful to develop a surrogate for animal skin, which could be use to predict flux through human skin. The fluxes (and physicochemical properties) of sunscreens and other compounds from propylene glycol (PG):water (AQ), 30:70, through human skin
Chromatograms
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