364517
L-色氨酸甲酯 盐酸盐
98%, for peptide synthesis
别名:
(S)-Tryptophan methyl ester hydrochloride, H-(L)-Trp-OMe hydrochloride, L-(-)-Tryptophan methyl ester hydrochloride, Tryptophan methyl ester hydrochloride
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所有图片(1)
About This Item
经验公式（希尔记法）:
C12H14N2O2 · HCl
CAS号:
分子量:
254.71
Beilstein:
4240280
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.22
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product name
L-色氨酸甲酯 盐酸盐, 98%
品質等級
化驗
98%
光學活性
[α]20/D +18°, c = 5 in methanol
反應適用性
reaction type: solution phase peptide synthesis
mp
218-220 °C (lit.)
應用
peptide synthesis
SMILES 字串
Cl.COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12
InChI
1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H/t10-;/m0./s1
InChI 密鑰
XNFNGGQRDXFYMM-PPHPATTJSA-N
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應用
L-色氨酸甲酯盐酸盐可用作制备以为物质的反应物：
- 通过与3,1-苯并恶嗪酮的酰化反应制备的 N-(2-氨基苯甲酰基)-L-色氨酸（二肽）的氨基草酰衍生物。
- 他达拉非（希爱力），其是一种5 型磷酸二酯酶（PDE5） 抑制剂。
- 异烟棒曲霉素C。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Christine Böttcher et al.
Journal of experimental botany, 62(12), 4267-4280 (2011-05-06)
Nine Gretchen Hagen (GH3) genes were identified in grapevine (Vitis vinifera L.) and six of these were predicted on the basis of protein sequence similarity to act as indole-3-acetic acid (IAA)-amido synthetases. The activity of these enzymes is thought to
Takeshi Miyazaki et al.
Journal of neurosurgery, 111(2), 230-237 (2009-02-10)
Indoleamine 2,3-dioxygenase (IDO), a kynurenine pathway (KP) enzyme catalyzing oxidation of the essential amino acid tryptophan (Trp), is thought to be involved in the immune resistance of malignant tumors through T-cell inactivation caused by Trp depletion and metabolite accumulation. Human
Haruki Nishizawa et al.
The journal of obstetrics and gynaecology research, 34(1), 1-6 (2008-01-30)
We have previously demonstrated that mRNA expression and enzyme activity levels of placental indoleamine 2,3-dioxygenase (IDO), which degrades L-tryptophan and blocks the proliferation of T cells, are significantly low in patients with severe pre-eclampsia. From this observation, we hypothesized that
Y Sakai et al.
Neurology, 70(6), 431-439 (2008-02-06)
Altered serotonin (5-HT) neurotransmission has been implicated in the pathophysiology of migraine headache. To test this hypothesis in migraine patients in vivo using PET and alpha-[(11)C]methyl-l-tryptophan as a surrogate marker of brain 5-HT synthetic rate during different phases of their
Michael Behen et al.
Movement disorders : official journal of the Movement Disorder Society, 22(15), 2256-2262 (2007-08-22)
Symptoms in Tourette syndrome (TS) are likely related to abnormalities involving multiple neurotransmitter systems in striatal-thalamo-cortical circuitry. Although prior studies have found abnormal levels of tryptophan, serotonin, and their metabolites in blood, cerebrospinal fluid and brain tissue of TS patients
Chromatograms
application for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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