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一般說明
N-Acetylcysteamine, also known as N-(2-Mercaptoethyl) acetamide, is a derivative of cysteamine, that is commonly used as a building block for the synthesis of alkylated thiol and thioesters via esterification.
應用
N-乙酰半胱氨酸可作为结构单元用于合成:
- N
- -乙酰半胱胺(SNAC)硫酯,通过在1,1′-羰二咪唑(CDI)参与下与多种酸衍生物反应。
- 噻吩并[2,3-c]吡咯衍生物,通过2-乙酰基-3-噻吩甲醛和各种胺的三组分反应。
- 碳青霉烯是一类beta-内酰胺类抗生素。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
235.4 °F - closed cup
閃點(°C)
113 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
The Journal of organic chemistry, 63(20), 6947-6951 (2001-10-24)
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Isolation, properties, and regulation of a mitochondrial acyl coenzyme A thioesterase from pig heart.
The Journal of biological chemistry, 254(11), 4516-4523 (1979-06-10)
Biochemical and biophysical research communications, 131(2), 786-792 (1985-09-16)
The acetyl transacylase activity of the fatty acid synthase from yeast has been investigated using p-nitrophenylthiol acetate. The chromophoric nature of the nitrophenylthiol moiety affords a convenient spectrophotometric assay for the transacylase function as well as a means to investigate
Tetrahedron Letters, 29, 4305-4305 (1988)
Organic letters, 8(1), 135-138 (2005-12-31)
[structure: see text] The enantioselective total synthesis of the N-acetylcysteamine thioester of seco-proansamitocin, a key biosynthetic intermediate of the highly potent antitumor agent ansamitocin, is described, which twice utilizes the Nagao acetate aldol reaction, as well as an indium-mediated alkynylation
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