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品質等級
化驗
97%
形狀
liquid
bp
142 °C/15 mmHg (lit.)
mp
13 °C (lit.)
密度
1.14 g/mL at 25 °C (lit.)
SMILES 字串
c1ccc(cc1)-n2ccnc2
InChI
1S/C9H8N2/c1-2-4-9(5-3-1)11-7-6-10-8-11/h1-8H
InChI 密鑰
SEULWJSKCVACTH-UHFFFAOYSA-N
一般說明
1-苯基咪唑是咪唑衍生物。它在虹鳟鱼(虹鳟鱼)肝细胞中诱导 7-乙氧基试卤灵-O-脱乙基酶(EROD)活化。1-苯咪唑的 S(1)→S(0)跃迁已通过共振双光子电离在超声气流膨胀中进行了研究。据报道,1-苯基咪唑是牛脑和 Ghs 垂体细胞钙调蛋白依赖性一氧化氮合酶的抑制剂。
應用
1-苯基咪唑是一种研究其对牛脑一氧化氮合酶对瓜氨酸形成的影响的合适试剂。
訊號詞
Warning
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
235.4 °F - closed cup
閃點(°C)
113 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
Biochimica et biophysica acta. General subjects, 1863(2), 304-312 (2018-11-06)
The camphor-degrading microorganism, Pseudomonas putida strain ATCC 17453, is an aerobic, gram-negative soil bacterium that uses camphor as its sole carbon and energy source. The genes responsible for the catabolic degradation of camphor are encoded on the extra-chromosomal CAM plasmid.
Active-site structure analysis of recombinant human inducible nitric oxide synthase using imidazole.
Biochemistry, 35(29), 9567-9575 (1996-07-23)
Nitric oxide synthase catalyzes the pyridine nucleotide-dependent oxidation of L-arginine to nitric oxide and L-citrulline. It is a specialized cytochrome P450 monooxygenase that is sensitive to inhibition by imidazole. Steady-state kinetic studies on recombinant human inducible nitric oxide synthase (rH-iNOS)
Biochemical pharmacology, 36(8), 1251-1260 (1987-04-15)
The nature of the cytochrome P-450-dependent enzyme reactions giving rise to four primary metabolites of caffeine was investigated using microsomes isolated from livers of human kidney donors. Metabolite formation proceeded at a lower rate than that predicted from in vivo
Journal of cancer research and clinical oncology, 111(3), 196-202 (1986-01-01)
The effect of the mixed-function oxidase inhibitor phenylimidazole (PI) and the amine oxidase inhibitors iproniazid (IPRO) and aminoacetonitrile (AAN) on the mutagenic activity of various carcinogens was determined in intrasanguineous host-mediated assays, using mice as hosts and E. coli 343/113
Toxicology and applied pharmacology, 149(2), 217-225 (1998-05-08)
Chloroform is carcinogenic in rodents but is not mutagenic or DNA reactive. Chloroform-induced hepatocarcinogenesis in rodents is believed to be secondary to events associated with cytotoxicity and cell proliferation. Understanding the mechanisms of chloroform toxicity may provide insights into the
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