324906

4,5,6,7-四氢吲哚

98%

• 别名: 2,3-Tetramethylenepyrrole, Cyclohex[b]pyrrole, NSC 122455
• 经验公式（希尔记法）: C₈H₁₁N
• CAS号: 13618-91-2
• 分子量: 121.18
• Beilstein: 108853
• MDL號碼: MFCD00012134
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24859477
• NACRES: NA.22

属性

• 化驗: 98%
• 形狀: solid
• mp: 53-57 °C (lit.)
• 儲存溫度: 2-8°C
• SMILES 字串: C1CCc2[nH]ccc2C1
• InChI: 1S/C8H11N/c1-2-4-8-7(3-1)5-6-9-8/h5-6,9H,1-4H2
• InChI 密鑰: KQBVVLOYXDVATK-UHFFFAOYSA-N

说明

一般說明

4,5,6,7-Tetrahydroindoles, due to their easy aromatization, are good intermediates to synthesize indoles. 4,5,6,7-Tetrahydroindole on condensation with cyanoacetate leads to 1-ethylthio-2-cyano-4,5,6,7-tetrahydrocyclohexa-[c]-3H-pyrrolizin-3-one.

應用

4,5,6,7-Tetrahydroindole was used as reactant in:

• synthesis of ethyl 3-(4,5,6,7-tetrahydroindol-2-yl)-2-propynoate
• preparation of BODIPY dyes
• N-alkylation with chloromethyloxirane
• preparation of hydroindolepropynoate by chemo- and regioselective solvent-free ethynylation
• palladium- and copper-free cross-coupling of halopropynoates
• preparation of carbonylalkenyl indoles via coupling with dicarbonyl compounds
• 1:2 annelation of 4,5,6,7-tetrahydroindole with 1-benzoyl-2-phenylacetylene

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves