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品質等級
化驗
97%
折射率
n20/D 1.4268 (lit.)
bp
50-53 °C/5 mmHg (lit.)
密度
0.896 g/mL at 25 °C (lit.)
儲存溫度
2-8°C
SMILES 字串
CC1(C)OB(CC=C)OC1(C)C
InChI
1S/C9H17BO2/c1-6-7-10-11-8(2,3)9(4,5)12-10/h6H,1,7H2,2-5H3
InChI 密鑰
YMHIEPNFCBNQQU-UHFFFAOYSA-N
一般說明
烯丙基硼酸季戊醇酯在简单酮亚胺的催化烯丙基化反应中被用作亲核试剂。
應用
作为试剂用于以下反应
试剂用于制备
- 钯催化的铃木宫村交叉偶联反应和烯烃复分解
- 分子间自由基加成
- 手性螺二茚二醇(SPINOL)基磷酸催化醛烯丙基化
- 钴催化二烯与烯烃的区域选择性加氢乙烯基化
- 核酸模板能量转移导致光释放反应
- 立体选择性铟催化的Hosomi-Sakurai反应
试剂用于制备
- 环砜羟乙胺作为BACE1抑制剂减少淀粉样蛋白β-肽
- 碳烯碘化钌与银羧酸盐的金属转移,得到碳氢活化的钌碳烯配合物作为Z选择性烯烃复分解的催化剂
- 烯丙基硼化试剂,用于制备烯丙醇和高烯丙基胺。
訊號詞
Warning
危險聲明
危險分類
Flam. Liq. 3
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
114.8 °F - closed cup
閃點(°C)
46 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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A catalytic asymmetric borono variant of Hosomi-Sakurai reactions with N,O-aminals.
Angewandte Chemie (International ed. in English), 50(47), 11121-11124 (2011-10-07)
Journal of medicinal chemistry, 55(7), 3364-3386 (2012-03-03)
Structure-based design of a series of cyclic hydroxyethylamine BACE1 inhibitors allowed the rational incorporation of prime- and nonprime-side fragments to a central core template without any amide functionality. The core scaffold selection and the structure-activity relationship development were supported by
Gaining absolute control of the regiochemistry in the cobalt-catalyzed 1,4-hydrovinylation reaction.
Organic letters, 13(23), 6236-6239 (2011-11-02)
The absolute control of the regiochemistry of a cobalt-catalyzed 1,4-hydrovinylation reaction is achieved by alternation of the ligands applied. While the dppe/dppp ligands led to the formation of the branched product, the herein described application of the SchmalzPhos ligand generates
Organometallics, 2, 230-230 (1983)
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