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Merck

303208

Sigma-Aldrich

溴甲基乙酸酯

95%

别名:

乙酰氧基甲基溴

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About This Item

线性分子式:
CH3CO2CH2Br
CAS号:
分子量:
152.97
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

95%

形狀

liquid

折射率

n20/D 1.447 (lit.)

bp

130-133 °C/750 mmHg (lit.)

密度

1.56 g/mL at 25 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

CC(=O)OCBr

InChI

1S/C3H5BrO2/c1-3(5)6-2-4/h2H2,1H3

InChI 密鑰

NHYXMAKLBXBVEO-UHFFFAOYSA-N

一般說明

人们在体外研究了溴甲基乙酸酯与 O(6)-烷基鸟嘌呤-DNA 烷基转移酶(DNA 修复蛋白)的相互作用。

應用

乙酸溴甲酯用于合成旋光的环己烯防腐剂,(6R)-6- [N-(2-氯-4-氟苯基)氨磺酰基]环己-1-烯-1-羧酸乙酯[(R)-1:TAK-242)]。它还作为试剂,用在钐二碘化物介导酮和醛转化为 1,2-二乙酸酯的过程中。

象形圖

FlameExclamation mark

訊號詞

Warning

危險分類

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

134.6 °F - closed cup

閃點(°C)

57 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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A direct preparation of 1, 2-diacetates from aldehydes and ketones promoted by samarium diiodide.
Enholm EJ and Satici H.
Tetrahedron Letters, 32(22), 2433-2436 (1991)
Masami Yamada et al.
Chemical & pharmaceutical bulletin, 54(1), 58-62 (2006-01-06)
Two new synthetic methods were established for the efficient synthesis of optically active cyclohexene antisepsis agent, ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate [(R)-1: TAK-242)]. The first method involved recrystallization from methanol of the diastereomeric mixture (6RS,1'R)-7, obtained by esterification of carboxylic acid 3 with
Liping Liu et al.
Chemical research in toxicology, 17(6), 742-752 (2004-06-23)
O(6)-Alkylguanine-DNA alkyltransferase (AGT) is a DNA repair protein that removes O(6)-alkylguanine adducts. The interaction of dibromomethane (CH(2)Br(2)) and bromomethyl acetate (BrCH(2)OAc) with AGT was studied in vitro, and the effect of AGT on their toxicity and mutagenicity was investigated using

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