化驗
≥97%
形狀
liquid
折射率
n20/D 1.398 (lit.)
bp
143-147 °C (lit.)
密度
0.976 g/mL at 25 °C (lit.)
SMILES 字串
COC(OC)C(C)=O
InChI
1S/C5H10O3/c1-4(6)5(7-2)8-3/h5H,1-3H3
InChI 密鑰
ULVSHNOGEVXRDR-UHFFFAOYSA-N
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應用
在 H 2 SO 4 存在下，甲基乙二醛 1,1-二甲基缩醛通过水解合成甲基乙二醛。用于考察甲基乙二醛介导的糖基化对酵母烯醇化酶 在 体内的结构、热稳定性和酶活性的影响 。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
78.8 °F - closed cup
閃點（°C）
26 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
K Ispolnov et al.
Journal of applied microbiology, 104(4), 1092-1102 (2008-01-16)
The purpose of this study was to investigate the behaviour of Saccharomyces cerevisiae in response to extracellular methylglyoxal. Cell survival to methylglyoxal and the importance of phosphates was investigated. The role of methylglyoxal detoxification systems and methylglyoxal-derived protein glycation were
Protein glycation in Saccharomyces cerevisiae. Argpyrimidine formation and methylglyoxal catabolism.
Ricardo A Gomes et al.
The FEBS journal, 272(17), 4521-4531 (2005-09-01)
Methylglyoxal is the most important intracellular glycation agent, formed nonenzymatically from triose phosphates during glycolysis in eukaryotic cells. Methylglyoxal-derived advanced glycation end-products are involved in neurodegenerative disorders (Alzheimer's, Parkinson's and familial amyloidotic polyneurophathy) and in the clinical complications of diabetes.
Ajit Ghosh et al.
Scientific reports, 6, 18358-18358 (2016-01-07)
Glyoxalase pathway, comprising glyoxalase I (GLY I) and glyoxalase II (GLY II) enzymes, is the major pathway for detoxification of methylglyoxal (MG) into D-lactate involving reduced glutathione (GSH). However, in bacteria, glyoxalase III (GLY III) with DJ-1/PfpI domain(s) can do
Svetlana I Dorovskikh et al.
Biomedicines, 9(8) (2021-08-28)
This work is aimed at developing the modification of the surface of medical implants with film materials based on noble metals in order to improve their biological characteristics. Gas-phase transportation methods were proposed to obtain such materials. To determine the
Daniel Prantner et al.
Journal of leukocyte biology, 109(3), 605-619 (2020-07-18)
The highly reactive compound methylglyoxal (MG) can cause direct damage to cells and tissues by reacting with cellular macromolecules. MG has been identified as a biomarker associated with increased sepsis-induced mortality. Patients undergoing septic shock have significantly elevated circulating MG
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