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Merck

148776

Sigma-Aldrich

3-羟基邻氨基苯甲酸

97%, for peptide synthesis

别名:

3-羟基邻氨基苯甲酸

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About This Item

线性分子式:
HOC6H3(NH2)CO2H
CAS号:
分子量:
153.14
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.22

product name

3-羟基邻氨基苯甲酸, 97%

化驗

97%

形狀

solid

反應適用性

reaction type: solution phase peptide synthesis

mp

240 °C (dec.) (lit.)

應用

peptide synthesis

SMILES 字串

Nc1c(O)cccc1C(O)=O

InChI

1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)

InChI 密鑰

WJXSWCUQABXPFS-UHFFFAOYSA-N

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一般說明

3-羟基邻氨基苯甲酸是一种氨基苯甲酸,通常用作各种化学反应的中间体。

應用

<ul>
<li><strong>Direct enzyme inhibition to mitigate quinolinic acid formation:</strong> Used to synthesize 2-amino-3-carboxymuconic semialdehyde (ACMS) during the kynurenine pathway of Tryptophan catabolism (Sanz et al., 2022).</li>
</ul>

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Phenolic esters like chlorogenic acid play an important role in therapeutic properties of many plant extracts. We aimed to produce phenolic esters in baker's yeast, by expressing tobacco 4CL and globe artichoke HCT. Indeed yeast produced phenolic esters. However, the
Raf Brouns et al.
Neurochemical research, 35(9), 1315-1322 (2010-05-22)
Post-stroke inflammation may induce upregulation of the kynurenine (KYN) pathway for tryptophan (TRP) oxidation, resulting in neuroprotective (kynurenic acid, KA) and neurotoxic metabolites (3-hydroxyanthranillic acid, 3-HAA). We investigated whether activity of the kynurenine pathway in acute ischemic stroke is related
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Cytokine induction of the enzyme indoleamine 2,3-dioxygenase (IDO) has been implicated in the development of major depressive disorder (MDD). IDO metabolizes tryptophan (TRP) into kynurenine (KYN), thereby decreasing TRP availability to the brain. KYN is further metabolized into several neurotoxins.

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