蒸汽密度
3.9 (vs air)
蒸汽壓力
60 mmHg ( 41.5 °C)
化驗
98%
折射率
n20/D 1.453 (lit.)
bp
105-106 °C (lit.)
mp
−22 °C (lit.)
密度
1.418 g/mL at 25 °C (lit.)
SMILES 字串
ClCC(Cl)=O
InChI
1S/C2H2Cl2O/c3-1-2(4)5/h1H2
InChI 密鑰
VGCXGMAHQTYDJK-UHFFFAOYSA-N
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一般說明
氯乙酰氯被用作氯化试剂、酰化试剂、单氯酮烯的前体,以及环化的合成砌块。
氯乙酰氯在合成二级胺取代的氰基吡唑啉衍生物过程中引起氰基吡唑啉的酰化。
氯乙酰氯在合成二级胺取代的氰基吡唑啉衍生物过程中引起氰基吡唑啉的酰化。
應用
氯乙酰氯可用于聚(甲基丙烯酸缩水甘油酯)的氯乙酰化和化学改性。氯乙酰氯用于研究大鼠和人肝微粒体对氯乙酰胺除草剂的体外代谢。氯乙酰氯用于合成一些具有抗利什曼原虫活性的新型喹啉衍生物。
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A - STOT RE 1
標靶器官
Lungs
安全危害
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
212.0 °F - closed cup
閃點(°C)
100 °C - closed cup
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Some novel quinoline derivatives were prepared and tested for antileishmanial activity. 2-(2-Methylquinolin-4-ylamino)-N-phenylacetamide (2) was found to be significantly more active than the standard antileishmanial drug sodium antimony gluconate (SAG) in reducing the parasite load both in the spleen and liver
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