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品質等級
化驗
97%
mp
174-177 °C (lit.)
SMILES 字串
Nc1nccnn1
InChI
1S/C3H4N4/c4-3-5-1-2-6-7-3/h1-2H,(H2,4,5,7)
InChI 密鑰
MJIWQHRXSLOUJN-UHFFFAOYSA-N
一般說明
3-amino-1,2,4-triazine (ATN) acts as a single molecular carbon nitride precursor during the preparation of mesoporous carbon nitride with high nitrogen content via polymerization. Additionally, it is also used in the synthesis of organometal complexes.
應用
- 药物应用中的抗肿瘤活性：一项研究报道了作为PDK1抑制剂的一系列新型3-氨基-1,2,4-三氮唑衍生物的开发， 这些衍生物对胰腺导管腺癌有显著的抗肿瘤活性，这显示了其在肿瘤治疗中的潜力 （Carbone et al., 2023）。
- 结晶学结构分析：该研究详细描述了一种涉及3-氨基-1,2,4-三氮唑的复合物的晶体结构和 Hirshfeld表面分析，提供了有关材料科学和配位化学领域分子相互作用和潜在应用的见解（Sangeetha et al., 2018）。
- NMR技术中的催化应用：研究中使用3-氨基-1,2,4-三氮唑，通过SABRE技术实现了水中NMR的显著极化，表明了其在改善NMR灵敏度的作用及其在磁共振成像的用途 （Zeng et al., 2014）。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Grant Abernethy et al.
Journal of chromatography. A, 1285, 165-167 (2013-03-12)
A rapid liquid chromatography-mass spectrometry method to detect 3-amino-1,2,4-triazine (ATZ) in milk was developed as part of a programme to set up methods for detecting the economically motivated adulteration of raw milk with nitrogen-containing compounds. When ATZ was added to
Jirí Hanusek et al.
Organic & biomolecular chemistry, 5(3), 478-484 (2007-01-26)
Contrary to a previous report, the sulfurisation of phosphorus(III) derivatives by 3-amino-1,2,4-dithiazole-5-thione (xanthane hydride) does not yield carbon disulfide and cyanamide as the additional reaction products. The reaction of xanthane hydride with triphenyl phosphine or trimethyl phosphite yields triphenyl phosphine
J Kolls et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 205(3), 220-229 (1994-03-01)
Nitric oxide is believed to participate in nonspecific cellular immunity. Gram negative bacterial endotoxins increase the production of reactive nitrogen intermediates (RNI) in phagocytic cells by inducing the enzyme nitric oxide synthase II (NOS II). Anti-inflammatory glucocorticoids attenuate endotoxin-induced increases
Crystal structure of 3-amino-1,2,4-triazin-5(2H)-one.
Long-Chih Hwang et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 18(6), 723-724 (2002-06-27)
S S Greenberg et al.
Life sciences, 57(21), 1949-1961 (1995-01-01)
We evaluated the effect of in vivo and in vitro administration of nitro-containing and nitro-deficient L-arginine-derived nitric oxide (NO) synthase inhibitors on the measurement of NO in plasma, urine and HEPES buffered physiologic salt solution (PSS) by ozone chemiluminescence and
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