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Merck

MYC

v-myc avian myelocytomatosis viral oncogene homolog

别名:
MRTL, MYCC, bHLHe39, c-Myc
物种:
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), domestic guinea pig Myc (100724557), Domestic Rabbit MYC (100327265), sheep MYC (443447)
UniProtKB ID:
P01106, A8WFE7, P01107, Q14026
基因ID:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)

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ELISA

货号
说明
物种
RAB1379
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4702005
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
物种反应性
应用
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
M4439
Anti-c-Myc抗体，小鼠单克隆 小鼠抗, clone 9E10, purified from hybridoma cell culture,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
C3956
抗-c-Myc 兔抗, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
SAB4200742
抗 c-Myc过氧化物酶抗体，小鼠单克隆, clone 9E10, purified from hybridoma cell culture,
物种反应性
human
应用
immunohistochemistry
western blot
A7470
Anti-c-Myc 琼脂糖亲和凝胶 兔抗, affinity isolated antibody,
物种反应性
human
应用
affinity chromatography
immunoprecipitation (IP)

Proteins

货号
说明
物种
SRP2089
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
EHU021051
MISSION® esiRNA, targeting human MYC,
物种
human
EMU075291
MISSION® esiRNA, targeting mouse Myc,
物种
mouse