GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
别名:
物种:
Human GABRA4 (2557), Mouse Gabra4 (14397), Rat Gabra4 (140675), domestic guinea pig Gabra4 (100721252), naked mole-rat Gabra4 (101718327), sheep GABRA4 (101121776), Domestic Rabbit GABRA4 (100339882), chicken GABRA4 (422770), dog GABRA4 (482132), cow GABRA4 (282238)
UniProtKB ID:
基因ID:
- Human(2557) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
- Mouse(14397) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
- Rat(140675) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic guinea pig(100721252) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- naked mole-rat(101718327) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- sheep(101121776) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- Domestic Rabbit(100339882) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- chicken(422770) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- dog(482132) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- cow(282238) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic cat(101098052) gamma-aminobutyric acid (GABA) A receptor, alpha 4
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
货号
说明
物种
咪达唑仑标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
地西泮标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S398A-34,
物种反应性
human, mouse
应用
immunofluorescence
western blot
western blot
Anti-GABRA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, human
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-GABA A Receptor-Atto 390 antibody produced in mouse, clone S398A-34,
物种反应性
human, mouse
应用
immunofluorescence
western blot
western blot
Monoclonal Anti-GABA A Receptor-Horseradish Peroxidase antibody produced in mouse, clone S398A-34,
物种反应性
human, mouse
应用
immunofluorescence
western blot
western blot
Monoclonal Anti-GABA A Receptor-R-Phycoerythrin antibody produced in mouse, clone S398A-34,
物种反应性
human, mouse
应用
immunofluorescence
western blot
western blot